Drug interactions
Tamsulosin + Tazemetostat
Severity: Minor
Tamsulosin and Tazemetostat: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Tazemetostat is a weak to moderate CYP3A4 inducer and may reduce tamsulosin levels. The clinical effect is probably limited.
What this interaction means in plain words
Tamsulosin and Tazemetostat have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Tamsulosin belongs to Genitourinary; Tazemetostat belongs to Miscellaneous.
Why it happens
Tazemetostat induces CYP3A4, increasing tamsulosin metabolism.
What to do
Monitor urinary symptom control during tazemetostat therapy. Adjust the tamsulosin dose if efficacy declines.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Tamsulosin
- Alfuzosin + Tamsulosin Major
- Avanafil + Tamsulosin Major
- Ceritinib + Tamsulosin Major
- Clarithromycin + Tamsulosin Major
- Cobicistat + Tamsulosin Major
- Doxazosin + Tamsulosin Major
Other interactions of Tazemetostat
Frequently asked questions
Can I take Tamsulosin with Tazemetostat?
MediHelp rates the interaction as minor. Tamsulosin and Tazemetostat have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Tazemetostat is a weak to moderate CYP3A4 inducer and may reduce tamsulosin levels. The clinical effect is probably limited.
How serious is the interaction between Tamsulosin and Tazemetostat?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor urinary symptom control during tazemetostat therapy. Adjust the tamsulosin dose if efficacy declines.
What other medicines interact with Tamsulosin?
MediHelp also lists interactions of Tamsulosin with, for example, Alfuzosin, Avanafil, Ceritinib. The full list is on the Tamsulosin page.
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