Drug interactions
Tecovirimat + Ticagrelor
Severity: Minor
Tecovirimat and Ticagrelor: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Tecovirimat is a weak CYP3A4 inducer and may slightly lower ticagrelor exposure. The clinical impact is likely small but could reduce antiplatelet effect.
What this interaction means in plain words
Tecovirimat and Ticagrelor have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Tecovirimat belongs to Miscellaneous; Ticagrelor belongs to Cardiovascular.
Why it happens
Weak induction of CYP3A4 by tecovirimat increases ticagrelor metabolism.
What to do
No routine change is needed; monitor for ischemic events during the short tecovirimat course.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ticagrelor
- Itraconazole + Ticagrelor Contraindicated
- Ketoconazole + Ticagrelor Contraindicated
- Levoketoconazole + Ticagrelor Contraindicated
- Abciximab + Ticagrelor Major
- Abrocitinib + Ticagrelor Major
- Acalabrutinib + Ticagrelor Major
Other interactions of Tecovirimat
- Bosentan + Tecovirimat Moderate
- Cyclosporin + Tecovirimat Moderate
- Darunavir + Tecovirimat Moderate
- Ethinyl estradiol-drospirenone + Tecovirimat Moderate
- Ethinyl estradiol-levonorgestrel + Tecovirimat Moderate
- Glimepiride-pioglitazone + Tecovirimat Moderate
Frequently asked questions
Can I take Tecovirimat with Ticagrelor?
MediHelp rates the interaction as minor. Tecovirimat and Ticagrelor have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Tecovirimat is a weak CYP3A4 inducer and may slightly lower ticagrelor exposure. The clinical impact is likely small but could reduce antiplatelet effect.
How serious is the interaction between Tecovirimat and Ticagrelor?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine change is needed; monitor for ischemic events during the short tecovirimat course.
What other medicines interact with Ticagrelor?
MediHelp also lists interactions of Ticagrelor with, for example, Itraconazole, Ketoconazole, Levoketoconazole. The full list is on the Ticagrelor page.
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