Drug interactions
Tecovirimat + Vinblastine
Severity: Minor
Tecovirimat and Vinblastine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Tecovirimat is a weak CYP3A4 inducer and might slightly reduce vinblastine exposure. The clinical impact is expected to be small and short-lived given the short treatment course.
What this interaction means in plain words
Tecovirimat and Vinblastine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Tecovirimat belongs to Miscellaneous; Vinblastine belongs to Oncology.
Why it happens
Weak induction of CYP3A4 by tecovirimat increases vinblastine metabolism.
What to do
No adjustment is routinely required; monitor for reduced clinical response during the tecovirimat course.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Vinblastine
Other interactions of Tecovirimat
- Bosentan + Tecovirimat Moderate
- Cyclosporin + Tecovirimat Moderate
- Darunavir + Tecovirimat Moderate
- Ethinyl estradiol-drospirenone + Tecovirimat Moderate
- Ethinyl estradiol-levonorgestrel + Tecovirimat Moderate
- Glimepiride-pioglitazone + Tecovirimat Moderate
Frequently asked questions
Can I take Tecovirimat with Vinblastine?
MediHelp rates the interaction as minor. Tecovirimat and Vinblastine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Tecovirimat is a weak CYP3A4 inducer and might slightly reduce vinblastine exposure. The clinical impact is expected to be small and short-lived given the short treatment course.
How serious is the interaction between Tecovirimat and Vinblastine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No adjustment is routinely required; monitor for reduced clinical response during the tecovirimat course.
What other medicines interact with Vinblastine?
MediHelp also lists interactions of Vinblastine with, for example, Adenovirus types 4 and 7 live, Apalutamide, Atazanavir. The full list is on the Vinblastine page.
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