Drug interactions
Teduglutide + Thioridazine
Severity: Moderate
Teduglutide and Thioridazine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Teduglutide improves intestinal fluid absorption and may increase absorption of oral drugs. This could raise thioridazine exposure, which matters given its dose-related QT effects.
What this interaction means in plain words
Teduglutide and Thioridazine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Teduglutide belongs to Endocrine; Thioridazine belongs to Central Nervous System.
Why it happens
Increased intestinal absorptive capacity may enhance oral absorption of thioridazine.
What to do
Monitor for thioridazine adverse effects and ECG changes after starting teduglutide, and reduce the thioridazine dose if needed.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Thioridazine
- Abiraterone + Thioridazine Contraindicated
- Adagrasib + Thioridazine Contraindicated
- Amiodarone + Thioridazine Contraindicated
- Amisulpride + Thioridazine Contraindicated
- Amitriptyline + Thioridazine Contraindicated
- Amoxapine + Thioridazine Contraindicated
Other interactions of Teduglutide
- Chlordiazepoxide + Teduglutide Moderate
- Clonazepam + Teduglutide Moderate
- Colchicine + Teduglutide Moderate
- Cyclosporin + Teduglutide Moderate
- Digoxin + Teduglutide Moderate
- Ethosuximide + Teduglutide Moderate
Frequently asked questions
Can I take Teduglutide with Thioridazine?
MediHelp rates the interaction as moderate. Teduglutide and Thioridazine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Teduglutide improves intestinal fluid absorption and may increase absorption of oral drugs. This could raise thioridazine exposure, which matters given its dose-related QT effects.
How serious is the interaction between Teduglutide and Thioridazine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for thioridazine adverse effects and ECG changes after starting teduglutide, and reduce the thioridazine dose if needed.
What other medicines interact with Thioridazine?
MediHelp also lists interactions of Thioridazine with, for example, Abiraterone, Adagrasib, Amiodarone. The full list is on the Thioridazine page.
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