Drug interactions
Tinidazole + Voriconazole
Severity: Minor
Tinidazole and Voriconazole: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Tinidazole is partly metabolized by CYP3A4, so voriconazole may modestly raise its levels. Clinical consequences are not well documented and are likely limited to more adverse effects such as nausea or metallic taste.
What this interaction means in plain words
Tinidazole and Voriconazole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Tinidazole belongs to Anti Parasitic; Voriconazole belongs to Anti Fungals.
Why it happens
Voriconazole inhibits CYP3A4, which contributes to tinidazole metabolism.
What to do
No routine dose change is needed; monitor for gastrointestinal and neurological adverse effects of tinidazole during a prolonged course.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Voriconazole
- Avanafil + Voriconazole Contraindicated
- Butabarbital + Voriconazole Contraindicated
- Carbamazepine + Voriconazole Contraindicated
- Conivaptan + Voriconazole Contraindicated
- Dihydroergotamine intranasal + Voriconazole Contraindicated
- Dihydroergotamine + Voriconazole Contraindicated
Other interactions of Tinidazole
- Disulfiram + Tinidazole Contraindicated
- Ethanol + Tinidazole Major
- Fexinidazole + Tinidazole Major
- Lopinavir + Tinidazole Major
- Nilotinib + Tinidazole Major
- Ritonavir + Tinidazole Major
Frequently asked questions
Can I take Tinidazole with Voriconazole?
MediHelp rates the interaction as minor. Tinidazole and Voriconazole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Tinidazole is partly metabolized by CYP3A4, so voriconazole may modestly raise its levels. Clinical consequences are not well documented and are likely limited to more adverse effects such as nausea or metallic taste.
How serious is the interaction between Tinidazole and Voriconazole?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine dose change is needed; monitor for gastrointestinal and neurological adverse effects of tinidazole during a prolonged course.
What other medicines interact with Voriconazole?
MediHelp also lists interactions of Voriconazole with, for example, Avanafil, Butabarbital, Carbamazepine. The full list is on the Voriconazole page.
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