Drug interactions
Tolmetin + Travoprost
Severity: Minor
Tolmetin and Travoprost: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ophthalmic prostaglandin analogs and systemic NSAIDs might influence intraocular pressure control, but the reports conflict and no consistent clinically important effect has been established.
What this interaction means in plain words
Tolmetin and Travoprost have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Tolmetin belongs to Musculoskeletal; Travoprost belongs to Miscellaneous.
Why it happens
NSAIDs inhibit prostaglandin synthesis, which could theoretically alter the uveoscleral outflow effect of travoprost; evidence is inconsistent.
What to do
No routine change is needed; check intraocular pressure at usual follow-up visits.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Tolmetin
- Ketorolac intranasal + Tolmetin Contraindicated
- Ketorolac + Tolmetin Contraindicated
- Aceclofenac + Tolmetin Major
- Acemetacin + Tolmetin Major
- Alteplase + Tolmetin Major
- Amlodipine-hydrochlorothiazide-valsartan + Tolmetin Major
Other interactions of Travoprost
- Bimatoprost + Travoprost Moderate
- Latanoprostene bunod + Travoprost Moderate
- Latanoprost + Travoprost Moderate
- Tafluprost + Travoprost Moderate
- Celecoxib + Travoprost Minor
- Diclofenac + Travoprost Minor
Frequently asked questions
Can I take Tolmetin with Travoprost?
MediHelp rates the interaction as minor. Tolmetin and Travoprost have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Ophthalmic prostaglandin analogs and systemic NSAIDs might influence intraocular pressure control, but the reports conflict and no consistent clinically important effect has been established.
How serious is the interaction between Tolmetin and Travoprost?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine change is needed; check intraocular pressure at usual follow-up visits.
What other medicines interact with Tolmetin?
MediHelp also lists interactions of Tolmetin with, for example, Ketorolac intranasal, Ketorolac, Aceclofenac. The full list is on the Tolmetin page.
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