Drug interactions
Torsemide + Treprostinil
Severity: Moderate
Torsemide and Treprostinil: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Treprostinil is a vasodilator and can lower blood pressure. Combined with torsemide, additive hypotension may occur, particularly with volume depletion.
What this interaction means in plain words
Torsemide and Treprostinil can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Torsemide belongs to Cardiovascular; Treprostinil belongs to Cardiovascular.
Why it happens
Additive pharmacodynamic hypotensive effects from vasodilation and diuretic-induced volume reduction.
What to do
Monitor blood pressure and volume status when starting or titrating either drug, and reduce the diuretic dose if symptomatic hypotension occurs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Torsemide
Other interactions of Treprostinil
Frequently asked questions
Can I take Torsemide with Treprostinil?
MediHelp rates the interaction as moderate. Torsemide and Treprostinil can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Treprostinil is a vasodilator and can lower blood pressure. Combined with torsemide, additive hypotension may occur, particularly with volume depletion.
How serious is the interaction between Torsemide and Treprostinil?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and volume status when starting or titrating either drug, and reduce the diuretic dose if symptomatic hypotension occurs.
What other medicines interact with Torsemide?
MediHelp also lists interactions of Torsemide with, for example, Amikacin, Amiodarone, Carbenoxolone. The full list is on the Torsemide page.
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