Drug interactions
Triclabendazole + Triptorelin
Severity: Moderate
Triclabendazole and Triptorelin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Triclabendazole may prolong the QT interval, and triptorelin has a similar effect. Combined use may increase the risk of ventricular arrhythmias, particularly in patients with other risk factors.
What this interaction means in plain words
Triclabendazole and Triptorelin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Triclabendazole belongs to Anti Parasitic; Triptorelin belongs to Endocrine.
Why it happens
Additive pharmacodynamic QT prolongation.
What to do
Check a baseline ECG and correct electrolytes. Triclabendazole is given for only a short course, so monitor for symptoms and repeat ECG if cardiac risk factors are present.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Triptorelin
Other interactions of Triclabendazole
Frequently asked questions
Can I take Triclabendazole with Triptorelin?
MediHelp rates the interaction as moderate. Triclabendazole and Triptorelin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Triclabendazole may prolong the QT interval, and triptorelin has a similar effect. Combined use may increase the risk of ventricular arrhythmias, particularly in patients with other risk factors.
How serious is the interaction between Triclabendazole and Triptorelin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check a baseline ECG and correct electrolytes. Triclabendazole is given for only a short course, so monitor for symptoms and repeat ECG if cardiac risk factors are present.
What other medicines interact with Triptorelin?
MediHelp also lists interactions of Triptorelin with, for example, Amisulpride, Arsenic trioxide, Bedaquiline. The full list is on the Triptorelin page.
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