تداخل‌های دارویی
Amoxicillin-clavulanic acid + Valoctocogene roxaparvovec
شدت: متوسط
Amoxicillin-clavulanic acid and Valoctocogene roxaparvovec: moderate interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Valoctocogene roxaparvovec commonly causes transaminase elevations after infusion. Amoxicillin-clavulanate is a recognized cause of drug-induced liver injury, so the combination may add to hepatic risk or confound interpretation of liver enzyme rises.
معنای این تداخل به زبان ساده
Amoxicillin-clavulanic acid and Valoctocogene roxaparvovec can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amoxicillin-clavulanic acid belongs to Anti Bacterial; Valoctocogene roxaparvovec belongs to Miscellaneous.
چرا رخ می‌دهد
Additive hepatotoxic potential from gene therapy-related hepatitis and clavulanate-associated idiosyncratic liver injury.
اقدام لازم
Monitor ALT and other liver tests closely during and after gene therapy, and consider a non-hepatotoxic antibiotic when an alternative is suitable.
از داروساز چه بپرسید
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Amoxicillin-clavulanic acid و Valoctocogene roxaparvovec، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Amoxicillin-clavulanic acid
تداخلات دیگر Valoctocogene roxaparvovec
پرسش‌های متداول
Can I take Amoxicillin-clavulanic acid with Valoctocogene roxaparvovec?
MediHelp rates the interaction as moderate. Amoxicillin-clavulanic acid and Valoctocogene roxaparvovec can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Valoctocogene roxaparvovec commonly causes transaminase elevations after infusion. Amoxicillin-clavulanate is a recognized cause of drug-induced liver injury, so the combination may add to hepatic risk or confound interpretation of liver enzyme rises.
How serious is the interaction between Amoxicillin-clavulanic acid and Valoctocogene roxaparvovec?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ALT and other liver tests closely during and after gene therapy, and consider a non-hepatotoxic antibiotic when an alternative is suitable.
What other medicines interact with Amoxicillin-clavulanic acid?
MediHelp also lists interactions of Amoxicillin-clavulanic acid with, for example, Methotrexate, Pexidartinib, Pretomanid. The full list is on the Amoxicillin-clavulanic acid page.
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