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Nevirapine + Valoctocogene roxaparvovec

شدت: شدید

Nevirapine and Valoctocogene roxaparvovec: major interaction.

آخرین به‌روزرسانی

ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.

محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.

خلاصه

Valoctocogene roxaparvovec commonly causes elevated liver enzymes, and nevirapine is a known hepatotoxic drug. Combined use may increase the risk or severity of liver injury and could compromise the gene therapy outcome.

معنای این تداخل به زبان ساده

Nevirapine and Valoctocogene roxaparvovec can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.

Nevirapine belongs to Anti Virals; Valoctocogene roxaparvovec belongs to Miscellaneous.

سطح شواهد: Low

چرا رخ می‌دهد

Additive hepatotoxicity; nevirapine can cause hepatocellular injury independent of the gene therapy.

اقدام لازم

Monitor ALT and other liver tests frequently after gene therapy. Prefer an alternative antiretroviral to nevirapine where possible.

از داروساز چه بپرسید

  • Does the benefit of taking both outweigh the risk in my case?
  • Do I need any blood test, ECG or other check while on both?
  • What early warning signs should I watch for, and what should I do if they appear?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

ویژه اعضای Pro+

باز کردن کل صفحه

یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Nevirapine و Valoctocogene roxaparvovec، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.

پرسش‌های متداول

Can I take Nevirapine with Valoctocogene roxaparvovec?

MediHelp rates the interaction as major. Nevirapine and Valoctocogene roxaparvovec can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Valoctocogene roxaparvovec commonly causes elevated liver enzymes, and nevirapine is a known hepatotoxic drug. Combined use may increase the risk or severity of liver injury and could compromise the gene therapy outcome.

How serious is the interaction between Nevirapine and Valoctocogene roxaparvovec?

MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ALT and other liver tests frequently after gene therapy. Prefer an alternative antiretroviral to nevirapine where possible.

What other medicines interact with Nevirapine?

MediHelp also lists interactions of Nevirapine with, for example, Elbasvir / grazoprevir, Ranolazine, St john's wort. The full list is on the Nevirapine page.

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