تداخل‌های دارویی
Propylthiouracil + Valoctocogene roxaparvovec
شدت: شدید
Propylthiouracil and Valoctocogene roxaparvovec: major interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Valoctocogene roxaparvovec commonly raises liver enzymes, and propylthiouracil is a known cause of serious liver injury. Combined use may increase hepatotoxicity risk and can complicate interpretation of enzyme rises after gene therapy.
معنای این تداخل به زبان ساده
Propylthiouracil and Valoctocogene roxaparvovec can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Propylthiouracil belongs to Endocrine; Valoctocogene roxaparvovec belongs to Miscellaneous.
چرا رخ می‌دهد
Additive hepatotoxicity risk from propylthiouracil and gene therapy-related hepatocellular effects.
اقدام لازم
Prefer an alternative antithyroid agent such as methimazole where possible. If used, monitor ALT and other liver tests frequently.
از داروساز چه بپرسید
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Propylthiouracil و Valoctocogene roxaparvovec، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Propylthiouracil
تداخلات دیگر Valoctocogene roxaparvovec
پرسش‌های متداول
Can I take Propylthiouracil with Valoctocogene roxaparvovec?
MediHelp rates the interaction as major. Propylthiouracil and Valoctocogene roxaparvovec can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Valoctocogene roxaparvovec commonly raises liver enzymes, and propylthiouracil is a known cause of serious liver injury. Combined use may increase hepatotoxicity risk and can complicate interpretation of enzyme rises after gene therapy.
How serious is the interaction between Propylthiouracil and Valoctocogene roxaparvovec?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Prefer an alternative antithyroid agent such as methimazole where possible. If used, monitor ALT and other liver tests frequently.
What other medicines interact with Propylthiouracil?
MediHelp also lists interactions of Propylthiouracil with, for example, Carbamazepine, Clozapine, Methimazole. The full list is on the Propylthiouracil page.
تک‌نگاری کامل، دوزاژ و بررسی تداخل دارویی در برنامه MediHelp
مرجع کامل را باز کنید، تداخل چند دارو را بررسی کنید و از ابزارهای دوز در برنامه MediHelp استفاده کنید.
