تداخل‌های دارویی
Deflazacort + Somatrogon
شدت: متوسط
Deflazacort and Somatrogon: moderate interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
High-dose glucocorticoids can weaken the growth-promoting effect of growth hormone analogs. Growth hormone also inhibits cortisone-to-cortisol conversion, which may reveal adrenal insufficiency in patients on steroid replacement.
معنای این تداخل به زبان ساده
Deflazacort and Somatrogon can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Deflazacort belongs to Miscellaneous; Somatrogon belongs to Endocrine.
چرا رخ می‌دهد
Pharmacodynamic antagonism of growth hormone by glucocorticoids and growth hormone inhibition of 11-beta-HSD1.
اقدام لازم
Monitor growth and keep the glucocorticoid dose as low as clinically possible. Reassess adrenal replacement needs when somatrogon is initiated.
از داروساز چه بپرسید
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Deflazacort و Somatrogon، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Deflazacort
- Adenovirus types 4 and 7 live + Deflazacort منع مصرف
- Bcg vaccine live + Deflazacort منع مصرف
- Deflazacort + Influenza virus vaccine quadrivalent intranasal منع مصرف
- Deflazacort + Measles mumps and rubella vaccine منع مصرف
- Deflazacort + Measles mumps and rubella vaccine live منع مصرف
- Deflazacort + Measles mumps rubella and varicella vaccine live منع مصرف
تداخلات دیگر Somatrogon
پرسش‌های متداول
Can I take Deflazacort with Somatrogon?
MediHelp rates the interaction as moderate. Deflazacort and Somatrogon can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. High-dose glucocorticoids can weaken the growth-promoting effect of growth hormone analogs. Growth hormone also inhibits cortisone-to-cortisol conversion, which may reveal adrenal insufficiency in patients on steroid replacement.
How serious is the interaction between Deflazacort and Somatrogon?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor growth and keep the glucocorticoid dose as low as clinically possible. Reassess adrenal replacement needs when somatrogon is initiated.
What other medicines interact with Deflazacort?
MediHelp also lists interactions of Deflazacort with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Deflazacort page.
تک‌نگاری کامل، دوزاژ و بررسی تداخل دارویی در برنامه MediHelp
مرجع کامل را باز کنید، تداخل چند دارو را بررسی کنید و از ابزارهای دوز در برنامه MediHelp استفاده کنید.
