تداخل‌های دارویی
Ozanimod + Tranylcypromine
شدت: منع مصرف
Ozanimod and Tranylcypromine: contraindicated interaction.
آخرین به‌روزرسانی
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محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Ozanimod's metabolism involves MAO-B, and its active metabolites may inhibit MAO. Combination with MAO inhibitors could cause hypertensive crisis or altered ozanimod exposure. Labeling contraindicates concurrent use.
معنای این تداخل به زبان ساده
Ozanimod and Tranylcypromine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Ozanimod belongs to Central Nervous System; Tranylcypromine belongs to Central Nervous System.
چرا رخ می‌دهد
MAO inhibition alters ozanimod metabolite formation, and the metabolites may add MAO inhibition, risking adrenergic excess.
اقدام لازم
Do not co-administer. Allow at least 14 days between stopping either drug and starting the other, per labeling.
از داروساز چه بپرسید
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Ozanimod و Tranylcypromine، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Tranylcypromine
- 5-HTP + Tranylcypromine منع مصرف
- Amitriptyline + Tranylcypromine منع مصرف
- Amoxapine + Tranylcypromine منع مصرف
- Atomoxetine + Tranylcypromine منع مصرف
- Benzphetamine + Tranylcypromine منع مصرف
- Brimonidine + Tranylcypromine منع مصرف
تداخلات دیگر Ozanimod
- Isocarboxazid + Ozanimod منع مصرف
- Linezolid + Ozanimod منع مصرف
- Ozanimod + Phenelzine منع مصرف
- Ozanimod + Procarbazine منع مصرف
- Ozanimod + Rasagiline منع مصرف
- Ozanimod + Safinamide منع مصرف
پرسش‌های متداول
Can I take Ozanimod with Tranylcypromine?
MediHelp rates the interaction as contraindicated. Ozanimod and Tranylcypromine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Ozanimod's metabolism involves MAO-B, and its active metabolites may inhibit MAO. Combination with MAO inhibitors could cause hypertensive crisis or altered ozanimod exposure. Labeling contraindicates concurrent use.
How serious is the interaction between Ozanimod and Tranylcypromine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not co-administer. Allow at least 14 days between stopping either drug and starting the other, per labeling.
What other medicines interact with Tranylcypromine?
MediHelp also lists interactions of Tranylcypromine with, for example, 5-HTP, Amitriptyline, Amoxapine. The full list is on the Tranylcypromine page.
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