تداخلهای دارویی
Isocarboxazid + Ozanimod
شدت: منع مصرف
Isocarboxazid and Ozanimod: contraindicated interaction.
آخرین بهروزرسانی
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محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Ozanimod's active metabolites are formed and may inhibit MAO-B, and combining with a nonselective MAOI may raise the risk of hypertensive crisis or serotonin toxicity. Clinical interaction data are limited, but labeling advises against the combination.
معنای این تداخل به زبان ساده
Isocarboxazid and Ozanimod are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Isocarboxazid belongs to Central Nervous System; Ozanimod belongs to Central Nervous System.
چرا رخ میدهد
Additive MAO inhibition, with ozanimod metabolites contributing to MAO-B inhibition.
اقدام لازم
Do not co-administer; allow at least 14 days between stopping either agent and starting the other.
از داروساز چه بپرسید
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیههای کامل مدیریت Isocarboxazid و Ozanimod، یادداشتهای تکمیلی، جزئیات شواهد و بررسیکننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Isocarboxazid
- 5-HTP + Isocarboxazid منع مصرف
- Amitriptyline + Isocarboxazid منع مصرف
- Amobarbital + Isocarboxazid منع مصرف
- Amoxapine + Isocarboxazid منع مصرف
- Apraclonidine + Isocarboxazid منع مصرف
- Atomoxetine + Isocarboxazid منع مصرف
تداخلات دیگر Ozanimod
- Linezolid + Ozanimod منع مصرف
- Ozanimod + Phenelzine منع مصرف
- Ozanimod + Procarbazine منع مصرف
- Ozanimod + Rasagiline منع مصرف
- Ozanimod + Safinamide منع مصرف
- Ozanimod + Tranylcypromine منع مصرف
پرسشهای متداول
Can I take Isocarboxazid with Ozanimod?
MediHelp rates the interaction as contraindicated. Isocarboxazid and Ozanimod are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Ozanimod's active metabolites are formed and may inhibit MAO-B, and combining with a nonselective MAOI may raise the risk of hypertensive crisis or serotonin toxicity. Clinical interaction data are limited, but labeling advises against the combination.
How serious is the interaction between Isocarboxazid and Ozanimod?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not co-administer; allow at least 14 days between stopping either agent and starting the other.
What other medicines interact with Isocarboxazid?
MediHelp also lists interactions of Isocarboxazid with, for example, 5-HTP, Amitriptyline, Amobarbital. The full list is on the Isocarboxazid page.
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