تداخل‌های دارویی
Ozanimod + Procarbazine
شدت: منع مصرف
Ozanimod and Procarbazine: contraindicated interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Ozanimod's active metabolites are formed and cleared through pathways involving MAO-B, and the labeling advises against use with MAO inhibitors. Procarbazine's MAO inhibition could alter exposure to these metabolites and may raise the risk of a hypertensive reaction. Procarbazine also adds immunosuppression and myelosuppression to the effects of ozanimod.
معنای این تداخل به زبان ساده
Ozanimod and Procarbazine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Ozanimod belongs to Central Nervous System; Procarbazine belongs to Oncology.
چرا رخ می‌دهد
MAO inhibition may alter ozanimod metabolite exposure and increases the risk of a hypertensive reaction through added sympathomimetic effects.
اقدام لازم
Do not use together. Allow at least 14 days between stopping either drug and starting the other.
از داروساز چه بپرسید
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Ozanimod و Procarbazine، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Procarbazine
- Adenovirus types 4 and 7 live + Procarbazine منع مصرف
- Amitriptyline + Procarbazine منع مصرف
- Amoxapine + Procarbazine منع مصرف
- Atomoxetine + Procarbazine منع مصرف
- Bcg vaccine live + Procarbazine منع مصرف
- Brimonidine + Procarbazine منع مصرف
تداخلات دیگر Ozanimod
- Isocarboxazid + Ozanimod منع مصرف
- Linezolid + Ozanimod منع مصرف
- Ozanimod + Phenelzine منع مصرف
- Ozanimod + Rasagiline منع مصرف
- Ozanimod + Safinamide منع مصرف
- Ozanimod + Tranylcypromine منع مصرف
پرسش‌های متداول
Can I take Ozanimod with Procarbazine?
MediHelp rates the interaction as contraindicated. Ozanimod and Procarbazine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Ozanimod's active metabolites are formed and cleared through pathways involving MAO-B, and the labeling advises against use with MAO inhibitors. Procarbazine's MAO inhibition could alter exposure to these metabolites and may raise the risk of a hypertensive reaction. Procarbazine also adds immunosuppression and myelosuppression to the effects of ozanimod.
How serious is the interaction between Ozanimod and Procarbazine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use together. Allow at least 14 days between stopping either drug and starting the other.
What other medicines interact with Procarbazine?
MediHelp also lists interactions of Procarbazine with, for example, Adenovirus types 4 and 7 live, Amitriptyline, Amoxapine. The full list is on the Procarbazine page.
تک‌نگاری کامل، دوزاژ و بررسی تداخل دارویی در برنامه MediHelp
مرجع کامل را باز کنید، تداخل چند دارو را بررسی کنید و از ابزارهای دوز در برنامه MediHelp استفاده کنید.
