Interactions médicamenteuses
Acetylsalicylic acid + Prasugrel
Gravité: Majeure
Acetylsalicylic acid and Prasugrel: major interaction.
Dernière mise à jour
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Résumé
Aspirin and prasugrel are combined deliberately in acute coronary syndrome and after stenting, but together they substantially increase the risk of major and fatal bleeding. Risk is higher in elderly patients, those with low body weight, or with prior stroke.
Ce que signifie cette interaction, en termes simples
Acetylsalicylic acid and Prasugrel can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Acetylsalicylic acid belongs to Musculoskeletal; Prasugrel belongs to Cardiovascular.
Pourquoi elle survient
Additive platelet inhibition through irreversible COX-1 blockade (aspirin) and irreversible P2Y12 receptor blockade (prasugrel).
Conduite à tenir
Use only when indicated, keep aspirin at low maintenance dose, and monitor for bleeding and hemoglobin; limit duration according to guidelines and consider alternatives in high-bleeding-risk patients.
Questions à poser à votre pharmacien
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Autres interactions de Acetylsalicylic acid
- Acetylsalicylic acid + Ketorolac Contre-indiquée
- Acetylsalicylic acid + Ketorolac intranasal Contre-indiquée
- Abciximab + Acetylsalicylic acid Majeure
- Acemetacin + Acetylsalicylic acid Majeure
- Acetazolamide + Acetylsalicylic acid Majeure
- Acetylsalicylic acid + Alteplase Majeure
Autres interactions de Prasugrel
- Apixaban + Prasugrel Majeure
- Argatroban + Prasugrel Majeure
- Cangrelor + Prasugrel Majeure
- Celecoxib + Prasugrel Majeure
- Dabigatran etexilate + Prasugrel Majeure
- Dalteparin + Prasugrel Majeure
Questions fréquentes
Can I take Acetylsalicylic acid with Prasugrel?
MediHelp rates the interaction as major. Acetylsalicylic acid and Prasugrel can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Aspirin and prasugrel are combined deliberately in acute coronary syndrome and after stenting, but together they substantially increase the risk of major and fatal bleeding. Risk is higher in elderly patients, those with low body weight, or with prior stroke.
How serious is the interaction between Acetylsalicylic acid and Prasugrel?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use only when indicated, keep aspirin at low maintenance dose, and monitor for bleeding and hemoglobin; limit duration according to guidelines and consider alternatives in high-bleeding-risk patients.
What other medicines interact with Acetylsalicylic acid?
MediHelp also lists interactions of Acetylsalicylic acid with, for example, Ketorolac, Ketorolac intranasal, Abciximab. The full list is on the Acetylsalicylic acid page.
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Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
