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Interactions médicamenteuses

Amphotericin b liposomal + Oxaliplatin

Gravité: Modérée

Amphotericin b liposomal and Oxaliplatin: moderate interaction.

Dernière mise à jour

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Résumé

Amphotericin B can cause nephrotoxicity, electrolyte loss and infusion reactions. Oxaliplatin could add to renal or infusion-related problems, but the clinical data supporting this are limited.

Ce que signifie cette interaction, en termes simples

Amphotericin b liposomal and Oxaliplatin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Amphotericin b liposomal belongs to Anti Fungals; Oxaliplatin belongs to Oncology.

Niveau de preuve: Low

Pourquoi elle survient

Possible additive nephrotoxicity; the mechanism is not well established.

Conduite à tenir

Monitor renal function, potassium and magnesium during co-treatment. Watch for infusion reactions such as bronchospasm and hypotension.

Questions à poser à votre pharmacien

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Questions fréquentes

Can I take Amphotericin b liposomal with Oxaliplatin?

MediHelp rates the interaction as moderate. Amphotericin b liposomal and Oxaliplatin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Amphotericin B can cause nephrotoxicity, electrolyte loss and infusion reactions. Oxaliplatin could add to renal or infusion-related problems, but the clinical data supporting this are limited.

How serious is the interaction between Amphotericin b liposomal and Oxaliplatin?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor renal function, potassium and magnesium during co-treatment. Watch for infusion reactions such as bronchospasm and hypotension.

What other medicines interact with Oxaliplatin?

MediHelp also lists interactions of Oxaliplatin with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Oxaliplatin page.

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Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.

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