Interactions médicamenteuses
Azathioprine + Ublituximab
Gravité: Majeure
Azathioprine and Ublituximab: major interaction.
Dernière mise à jour
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Résumé
Ublituximab depletes B cells while azathioprine suppresses lymphocyte proliferation, so combined use may increase the risk of serious infections.
Ce que signifie cette interaction, en termes simples
Azathioprine and Ublituximab can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Azathioprine belongs to Gastrointestinal Tract; Ublituximab belongs to Miscellaneous.
Pourquoi elle survient
Additive immunosuppression from anti-CD20 B-cell depletion and azathioprine lymphocyte suppression.
Conduite à tenir
Avoid combining where possible, or monitor closely for infection and check blood counts regularly. Consider the duration of effect of each drug when sequencing therapy.
Questions à poser à votre pharmacien
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Autres interactions de Azathioprine
- Adenovirus types 4 and 7 live + Azathioprine Contre-indiquée
- Azathioprine + Bcg vaccine live Contre-indiquée
- Azathioprine + Febuxostat Contre-indiquée
- Azathioprine + Influenza virus vaccine quadrivalent intranasal Contre-indiquée
- Azathioprine + Measles mumps and rubella vaccine Contre-indiquée
- Azathioprine + Measles mumps and rubella vaccine live Contre-indiquée
Autres interactions de Ublituximab
- Baricitinib + Ublituximab Majeure
- Cyclosporin + Ublituximab Majeure
- Fingolimod + Ublituximab Majeure
- Leflunomide + Ublituximab Majeure
- Mercaptopurine + Ublituximab Majeure
- Natalizumab + Ublituximab Majeure
Questions fréquentes
Can I take Azathioprine with Ublituximab?
MediHelp rates the interaction as major. Azathioprine and Ublituximab can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Ublituximab depletes B cells while azathioprine suppresses lymphocyte proliferation, so combined use may increase the risk of serious infections.
How serious is the interaction between Azathioprine and Ublituximab?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combining where possible, or monitor closely for infection and check blood counts regularly. Consider the duration of effect of each drug when sequencing therapy.
What other medicines interact with Azathioprine?
MediHelp also lists interactions of Azathioprine with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Febuxostat. The full list is on the Azathioprine page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
