Interactions médicamenteuses
Benzathine penicillin g + Leniolisib
Gravité: Mineure
Benzathine penicillin g and Leniolisib: minor interaction.
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Résumé
Leniolisib inhibits OATP1B1 and OATP1B3, which could in theory increase levels of substrates. Penicillin G is not a clinically important OATP substrate and has a wide safety margin, so a meaningful effect is unlikely.
Ce que signifie cette interaction, en termes simples
Benzathine penicillin g and Leniolisib have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Benzathine penicillin g belongs to Anti Bacterial; Leniolisib belongs to Miscellaneous.
Pourquoi elle survient
Theoretical inhibition of hepatic OATP1B1/1B3 uptake by leniolisib.
Conduite à tenir
No dose change is needed. Monitor for penicillin adverse effects only if other risk factors exist.
Questions à poser à votre pharmacien
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Autres interactions de Benzathine penicillin g
- Benzathine penicillin g + Cholera vaccine Modérée
- Benzathine penicillin g + Microbiota Modérée
- Benzathine penicillin g + Omadacycline Modérée
- Benzathine penicillin g + Sodium picosulfate / magnesium oxide / anhydrous citric acid Modérée
- Benzathine penicillin g + Vadadustat Modérée
- Amifampridine + Benzathine penicillin g Mineure
Autres interactions de Leniolisib
- Amobarbital + Leniolisib Majeure
- Apalutamide + Leniolisib Majeure
- Carbamazepine + Leniolisib Majeure
- Clarithromycin + Leniolisib Majeure
- Cyclosporin + Leniolisib Majeure
- Efavirenz + Leniolisib Majeure
Questions fréquentes
Can I take Benzathine penicillin g with Leniolisib?
MediHelp rates the interaction as minor. Benzathine penicillin g and Leniolisib have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Leniolisib inhibits OATP1B1 and OATP1B3, which could in theory increase levels of substrates. Penicillin G is not a clinically important OATP substrate and has a wide safety margin, so a meaningful effect is unlikely.
How serious is the interaction between Benzathine penicillin g and Leniolisib?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is needed. Monitor for penicillin adverse effects only if other risk factors exist.
What other medicines interact with Benzathine penicillin g?
MediHelp also lists interactions of Benzathine penicillin g with, for example, Cholera vaccine, Microbiota, Omadacycline. The full list is on the Benzathine penicillin g page.
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