Interactions médicamenteuses
Cefotetan + Gentamicin
Gravité: Modérée
Cefotetan and Gentamicin: moderate interaction.
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Résumé
Concurrent use of cephalosporins with aminoglycosides has been associated with increased renal injury in some reports, although the effect is inconsistent for most agents. Risk is greatest in patients with renal impairment, older age or dehydration.
Ce que signifie cette interaction, en termes simples
Cefotetan and Gentamicin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cefotetan belongs to Anti Bacterial; Gentamicin belongs to Anti Bacterial.
Pourquoi elle survient
Possible additive proximal tubular injury; mechanism is not firmly established.
Conduite à tenir
Monitor renal function and gentamicin concentrations, and adjust doses according to creatinine clearance.
Questions à poser à votre pharmacien
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Autres interactions de Gentamicin
- Cidofovir + Gentamicin Contre-indiquée
- Adefovir + Gentamicin Majeure
- Amikacin + Gentamicin Majeure
- Amlodipine-hydrochlorothiazide-valsartan + Gentamicin Majeure
- Amphotericin b deoxycholate + Gentamicin Majeure
- Amphotericin b + Gentamicin Majeure
Autres interactions de Cefotetan
- Cefotetan + Dronabinol Contre-indiquée
- Cefotetan + Warfarin Majeure
- Amikacin + Cefotetan Modérée
- Argatroban + Cefotetan Modérée
- Cefotetan + Dalteparin Modérée
- Cefotetan + Enoxaparin Modérée
Questions fréquentes
Can I take Cefotetan with Gentamicin?
MediHelp rates the interaction as moderate. Cefotetan and Gentamicin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Concurrent use of cephalosporins with aminoglycosides has been associated with increased renal injury in some reports, although the effect is inconsistent for most agents. Risk is greatest in patients with renal impairment, older age or dehydration.
How serious is the interaction between Cefotetan and Gentamicin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor renal function and gentamicin concentrations, and adjust doses according to creatinine clearance.
What other medicines interact with Gentamicin?
MediHelp also lists interactions of Gentamicin with, for example, Cidofovir, Adefovir, Amikacin. The full list is on the Gentamicin page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
