Interactions médicamenteuses
Certolizumab pegol + Typhoid vaccine live
Gravité: Contre-indiquée
Certolizumab pegol and Typhoid vaccine live: contraindicated interaction.
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Résumé
Live oral typhoid vaccine contains attenuated Salmonella Typhi. TNF blockade with certolizumab could allow vaccine-strain infection and reduce vaccine response.
Ce que signifie cette interaction, en termes simples
Certolizumab pegol and Typhoid vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Pourquoi elle survient
TNF inhibition impairs host defence against replicating live bacteria.
Conduite à tenir
Use the inactivated Vi polysaccharide typhoid vaccine instead during certolizumab therapy.
Questions à poser à votre pharmacien
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Autres interactions de Certolizumab pegol
- Adenovirus types 4 and 7 live + Certolizumab pegol Contre-indiquée
- Bcg intravesical live + Certolizumab pegol Contre-indiquée
- Bcg vaccine live + Certolizumab pegol Contre-indiquée
- Certolizumab pegol + Influenza virus vaccine quadrivalent intranasal Contre-indiquée
- Certolizumab pegol + Measles mumps and rubella vaccine Contre-indiquée
- Certolizumab pegol + Measles mumps and rubella vaccine live Contre-indiquée
Questions fréquentes
Can I take Certolizumab pegol with Typhoid vaccine live?
MediHelp rates the interaction as contraindicated. Certolizumab pegol and Typhoid vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Live oral typhoid vaccine contains attenuated Salmonella Typhi. TNF blockade with certolizumab could allow vaccine-strain infection and reduce vaccine response.
How serious is the interaction between Certolizumab pegol and Typhoid vaccine live?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use the inactivated Vi polysaccharide typhoid vaccine instead during certolizumab therapy.
What other medicines interact with Certolizumab pegol?
MediHelp also lists interactions of Certolizumab pegol with, for example, Adenovirus types 4 and 7 live, Bcg intravesical live, Bcg vaccine live. The full list is on the Certolizumab pegol page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
