Interactions médicamenteuses
Deflazacort + Penicillin g
Gravité: Modérée
Deflazacort and Penicillin g: moderate interaction.
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Résumé
High-dose penicillin G can cause hypokalemia through delivery of a nonreabsorbable anion to the distal nephron, which increases potassium loss. Deflazacort, a corticosteroid, has mineralocorticoid activity that can also lower potassium, so the effects may add together.
Ce que signifie cette interaction, en termes simples
Deflazacort and Penicillin g can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Deflazacort belongs to Miscellaneous; Penicillin g belongs to Anti Bacterial.
Pourquoi elle survient
Additive renal potassium wasting from penicillin G and corticosteroid mineralocorticoid effect.
Conduite à tenir
Monitor serum potassium during high-dose penicillin G therapy with deflazacort and replace potassium as needed.
Questions à poser à votre pharmacien
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Autres interactions de Penicillin g
- Amifampridine + Penicillin g Modérée
- Amiloride + Penicillin g Modérée
- Bcg vaccine live + Penicillin g Modérée
- Cholera vaccine + Penicillin g Modérée
- Colestipol + Penicillin g Modérée
- Demeclocycline + Penicillin g Modérée
Autres interactions de Deflazacort
- Adenovirus types 4 and 7 live + Deflazacort Contre-indiquée
- Bcg vaccine live + Deflazacort Contre-indiquée
- Deflazacort + Influenza virus vaccine quadrivalent intranasal Contre-indiquée
- Deflazacort + Measles mumps and rubella vaccine Contre-indiquée
- Deflazacort + Measles mumps and rubella vaccine live Contre-indiquée
- Deflazacort + Measles mumps rubella and varicella vaccine live Contre-indiquée
Questions fréquentes
Can I take Deflazacort with Penicillin g?
MediHelp rates the interaction as moderate. Deflazacort and Penicillin g can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. High-dose penicillin G can cause hypokalemia through delivery of a nonreabsorbable anion to the distal nephron, which increases potassium loss. Deflazacort, a corticosteroid, has mineralocorticoid activity that can also lower potassium, so the effects may add together.
How serious is the interaction between Deflazacort and Penicillin g?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium during high-dose penicillin G therapy with deflazacort and replace potassium as needed.
What other medicines interact with Penicillin g?
MediHelp also lists interactions of Penicillin g with, for example, Amifampridine, Amiloride, Bcg vaccine live. The full list is on the Penicillin g page.
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Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
