Interactions médicamenteuses
Deflazacort + Sorbitol
Gravité: Modérée
Deflazacort and Sorbitol: moderate interaction.
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Résumé
Sorbitol has an osmotic laxative effect that can cause diarrhea and intestinal potassium loss, and deflazacort, a corticosteroid, can promote renal potassium excretion. Combined use may contribute to hypokalemia, mainly with repeated or large laxative doses.
Ce que signifie cette interaction, en termes simples
Deflazacort and Sorbitol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Deflazacort belongs to Miscellaneous; Sorbitol belongs to Gastrointestinal Tract.
Pourquoi elle survient
Additive potassium loss from osmotic diarrhea and corticosteroid mineralocorticoid-related kaliuresis.
Conduite à tenir
Monitor serum potassium if sorbitol is used repeatedly or in large amounts with deflazacort. Replace potassium as needed.
Questions à poser à votre pharmacien
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Autres interactions de Sorbitol
- Sodium polystyrene sulfonate + Sorbitol Majeure
- Lamivudine + Sorbitol Modérée
Autres interactions de Deflazacort
- Adenovirus types 4 and 7 live + Deflazacort Contre-indiquée
- Bcg vaccine live + Deflazacort Contre-indiquée
- Deflazacort + Influenza virus vaccine quadrivalent intranasal Contre-indiquée
- Deflazacort + Measles mumps and rubella vaccine Contre-indiquée
- Deflazacort + Measles mumps and rubella vaccine live Contre-indiquée
- Deflazacort + Measles mumps rubella and varicella vaccine live Contre-indiquée
Questions fréquentes
Can I take Deflazacort with Sorbitol?
MediHelp rates the interaction as moderate. Deflazacort and Sorbitol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Sorbitol has an osmotic laxative effect that can cause diarrhea and intestinal potassium loss, and deflazacort, a corticosteroid, can promote renal potassium excretion. Combined use may contribute to hypokalemia, mainly with repeated or large laxative doses.
How serious is the interaction between Deflazacort and Sorbitol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium if sorbitol is used repeatedly or in large amounts with deflazacort. Replace potassium as needed.
What other medicines interact with Sorbitol?
MediHelp also lists interactions of Sorbitol with, for example, Sodium polystyrene sulfonate, Lamivudine. The full list is on the Sorbitol page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
