Interactions médicamenteuses
Dexamethasone + Somatrogon
Gravité: Modérée
Dexamethasone and Somatrogon: moderate interaction.
Dernière mise à jour
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Résumé
High-dose glucocorticoids can attenuate the growth-promoting effect of growth hormone analogs such as somatrogon. Growth hormone may also reduce cortisol activation, altering glucocorticoid replacement needs.
Ce que signifie cette interaction, en termes simples
Dexamethasone and Somatrogon can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Dexamethasone belongs to Endocrine; Somatrogon belongs to Endocrine.
Pourquoi elle survient
Pharmacodynamic antagonism by glucocorticoids and growth hormone inhibition of 11-beta-HSD-1.
Conduite à tenir
Monitor growth response and adjust somatrogon dose as needed. Reassess glucocorticoid replacement dosing after initiation of somatrogon.
Questions à poser à votre pharmacien
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Autres interactions de Dexamethasone
- Bcg vaccine live + Dexamethasone Contre-indiquée
- Dexamethasone + Mifepristone Contre-indiquée
- Dexamethasone + Rilpivirine Contre-indiquée
- Dexamethasone + Smallpox vaccine live Contre-indiquée
- Dexamethasone + Varicella virus vaccine live Contre-indiquée
- Dexamethasone + Yellow fever vaccine Contre-indiquée
Autres interactions de Somatrogon
- Alogliptin-metformin + Somatrogon Modérée
- Alogliptin-pioglitazone + Somatrogon Modérée
- Alogliptin + Somatrogon Modérée
- Canagliflozin-metformin + Somatrogon Modérée
- Chlorpropamide + Somatrogon Modérée
- Cyclosporin + Somatrogon Modérée
Questions fréquentes
Can I take Dexamethasone with Somatrogon?
MediHelp rates the interaction as moderate. Dexamethasone and Somatrogon can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. High-dose glucocorticoids can attenuate the growth-promoting effect of growth hormone analogs such as somatrogon. Growth hormone may also reduce cortisol activation, altering glucocorticoid replacement needs.
How serious is the interaction between Dexamethasone and Somatrogon?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor growth response and adjust somatrogon dose as needed. Reassess glucocorticoid replacement dosing after initiation of somatrogon.
What other medicines interact with Dexamethasone?
MediHelp also lists interactions of Dexamethasone with, for example, Bcg vaccine live, Mifepristone, Rilpivirine. The full list is on the Dexamethasone page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
