Interactions médicamenteuses
Foscarnet + Zoledronic acid
Gravité: Modérée
Foscarnet and Zoledronic acid: moderate interaction.
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Résumé
Both drugs lower serum calcium: zoledronic acid by inhibiting bone resorption and foscarnet by chelating ionized calcium. Together they may cause symptomatic hypocalcemia, including tetany, paresthesias and seizures or arrhythmias.
Ce que signifie cette interaction, en termes simples
Foscarnet and Zoledronic acid can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Foscarnet belongs to Anti Virals; Zoledronic acid belongs to Musculoskeletal.
Pourquoi elle survient
Additive lowering of serum calcium through bone resorption inhibition and chelation of ionized calcium.
Conduite à tenir
Check calcium, magnesium and ionized calcium before and during therapy, and correct deficits. Replace calcium and vitamin D as needed.
Questions à poser à votre pharmacien
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Autres interactions de Zoledronic acid
Autres interactions de Foscarnet
- Cidofovir + Foscarnet Contre-indiquée
- Foscarnet + Pimozide Contre-indiquée
- Foscarnet + Thioridazine Contre-indiquée
- Foscarnet + Vandetanib Contre-indiquée
- Adagrasib + Foscarnet Majeure
- Adefovir + Foscarnet Majeure
Questions fréquentes
Can I take Foscarnet with Zoledronic acid?
MediHelp rates the interaction as moderate. Foscarnet and Zoledronic acid can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs lower serum calcium: zoledronic acid by inhibiting bone resorption and foscarnet by chelating ionized calcium. Together they may cause symptomatic hypocalcemia, including tetany, paresthesias and seizures or arrhythmias.
How serious is the interaction between Foscarnet and Zoledronic acid?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check calcium, magnesium and ionized calcium before and during therapy, and correct deficits. Replace calcium and vitamin D as needed.
What other medicines interact with Zoledronic acid?
MediHelp also lists interactions of Zoledronic acid with, for example, Amikacin, Bumetanide, Dichlorphenamide. The full list is on the Zoledronic acid page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
