Interactions médicamenteuses
Ixekizumab + Lomustine
Gravité: Modérée
Ixekizumab and Lomustine: moderate interaction.
Dernière mise à jour
Réservé aux professionnels de santé — à titre de référence uniquement. Cette page est un bref résumé, pas un avis médical, et ne remplace ni la notice officielle ni le jugement clinique. Vérifiez toujours avant de prescrire ou de délivrer.
Le contenu clinique de cette page n'est disponible qu'en anglais.
Résumé
Lomustine causes myelosuppression and immune suppression, while ixekizumab blocks IL-17A signaling and impairs host defense. Together they may raise the risk of serious bacterial, fungal or opportunistic infections.
Ce que signifie cette interaction, en termes simples
Ixekizumab and Lomustine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Ixekizumab belongs to Miscellaneous; Lomustine belongs to Oncology.
Pourquoi elle survient
Additive immunosuppression: cytotoxic marrow suppression plus IL-17A antagonism.
Conduite à tenir
Screen for active infection before and during therapy and monitor neutrophil counts. Hold ixekizumab if a serious infection develops.
Questions à poser à votre pharmacien
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Réservé aux membres Pro+
Débloquer la page complète
Créez un compte et lancez un essai Pro+ pour débloquer les conseils complets de prise en charge pour Ixekizumab et Lomustine, les notes complémentaires, le détail des données probantes et le vérificateur d'interactions pour une ordonnance complète.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Essayez Pro+ gratuitement pendant 7 jours sur le web. Sans carte.
Autres interactions de Lomustine
- Adenovirus types 4 and 7 live + Lomustine Contre-indiquée
- Bcg vaccine live + Lomustine Contre-indiquée
- Influenza virus vaccine quadrivalent intranasal + Lomustine Contre-indiquée
- Lomustine + Measles mumps and rubella vaccine Contre-indiquée
- Lomustine + Measles mumps and rubella vaccine live Contre-indiquée
- Lomustine + Measles mumps rubella and varicella vaccine live Contre-indiquée
Autres interactions de Ixekizumab
- Ixekizumab + Measles mumps and rubella vaccine Majeure
- Ixekizumab + Upadacitinib Majeure
- Ifosfamide + Ixekizumab Modérée
- Carbamazepine + Ixekizumab Mineure
- Cyclosporin + Ixekizumab Mineure
- Ethosuximide + Ixekizumab Mineure
Questions fréquentes
Can I take Ixekizumab with Lomustine?
MediHelp rates the interaction as moderate. Ixekizumab and Lomustine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Lomustine causes myelosuppression and immune suppression, while ixekizumab blocks IL-17A signaling and impairs host defense. Together they may raise the risk of serious bacterial, fungal or opportunistic infections.
How serious is the interaction between Ixekizumab and Lomustine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Screen for active infection before and during therapy and monitor neutrophil counts. Hold ixekizumab if a serious infection develops.
What other medicines interact with Lomustine?
MediHelp also lists interactions of Lomustine with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Lomustine page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
