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Interactions médicamenteuses

Ixekizumab + Measles mumps and rubella vaccine

Gravité: Majeure

Ixekizumab and Measles mumps and rubella vaccine: major interaction.

Dernière mise à jour

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Résumé

Live vaccines should be avoided during ixekizumab therapy because of uncertain vaccine response and safety. Ixekizumab selectively blocks IL-17A, so the risk of disseminated vaccine virus is likely low but not established.

Ce que signifie cette interaction, en termes simples

Ixekizumab and Measles mumps and rubella vaccine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.

Ixekizumab belongs to Miscellaneous; Measles mumps and rubella vaccine belongs to Miscellaneous.

Niveau de preuve: Low

Pourquoi elle survient

Immune modulation by ixekizumab may impair vaccine response and live vaccine safety.

Conduite à tenir

Complete live vaccinations before starting ixekizumab, ideally at least 4 weeks prior. Avoid live vaccines during treatment.

Questions à poser à votre pharmacien

  • Does the benefit of taking both outweigh the risk in my case?
  • Do I need any blood test, ECG or other check while on both?
  • What early warning signs should I watch for, and what should I do if they appear?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Questions fréquentes

Can I take Ixekizumab with Measles mumps and rubella vaccine?

MediHelp rates the interaction as major. Ixekizumab and Measles mumps and rubella vaccine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Live vaccines should be avoided during ixekizumab therapy because of uncertain vaccine response and safety. Ixekizumab selectively blocks IL-17A, so the risk of disseminated vaccine virus is likely low but not established.

How serious is the interaction between Ixekizumab and Measles mumps and rubella vaccine?

MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Complete live vaccinations before starting ixekizumab, ideally at least 4 weeks prior. Avoid live vaccines during treatment.

What other medicines interact with Measles mumps and rubella vaccine?

MediHelp also lists interactions of Measles mumps and rubella vaccine with, for example, Adalimumab, Anakinra, Antithymocyte globulin equine. The full list is on the Measles mumps and rubella vaccine page.

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Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.

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