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Interactions médicamenteuses

Ixekizumab + Upadacitinib

Gravité: Majeure

Ixekizumab and Upadacitinib: major interaction.

Dernière mise à jour

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Résumé

Both drugs suppress immune pathways, and combined use may raise the risk of serious infection. Combination therapy has not been studied and is not recommended.

Ce que signifie cette interaction, en termes simples

Ixekizumab and Upadacitinib can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.

Ixekizumab belongs to Miscellaneous; Upadacitinib belongs to Musculoskeletal.

Niveau de preuve: Low

Pourquoi elle survient

Additive immunosuppression through JAK inhibition and IL-17A blockade.

Conduite à tenir

Avoid combined use. If both are considered, monitor closely for infection.

Questions à poser à votre pharmacien

  • Does the benefit of taking both outweigh the risk in my case?
  • Do I need any blood test, ECG or other check while on both?
  • What early warning signs should I watch for, and what should I do if they appear?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Questions fréquentes

Can I take Ixekizumab with Upadacitinib?

MediHelp rates the interaction as major. Ixekizumab and Upadacitinib can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Both drugs suppress immune pathways, and combined use may raise the risk of serious infection. Combination therapy has not been studied and is not recommended.

How serious is the interaction between Ixekizumab and Upadacitinib?

MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combined use. If both are considered, monitor closely for infection.

What other medicines interact with Upadacitinib?

MediHelp also lists interactions of Upadacitinib with, for example, Abrocitinib, Adenovirus types 4 and 7 live, Baricitinib. The full list is on the Upadacitinib page.

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Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.

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