Interactions médicamenteuses
Cyclosporin + Ixekizumab
Gravité: Mineure
Cyclosporin and Ixekizumab: minor interaction.
Dernière mise à jour
Réservé aux professionnels de santé — à titre de référence uniquement. Cette page est un bref résumé, pas un avis médical, et ne remplace ni la notice officielle ni le jugement clinique. Vérifiez toujours avant de prescrire ou de délivrer.
Le contenu clinique de cette page n'est disponible qu'en anglais.
Résumé
Reduced inflammation during IL-17A blockade may restore CYP450 activity that was suppressed by cytokines, theoretically lowering cyclosporine concentrations. A clinically important effect has not been established. Combined immunosuppression also raises infection concerns.
Ce que signifie cette interaction, en termes simples
Cyclosporin and Ixekizumab have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Cyclosporin belongs to Miscellaneous; Ixekizumab belongs to Miscellaneous.
Pourquoi elle survient
Cytokine normalization may modestly increase CYP-mediated cyclosporine metabolism; this is theoretical.
Conduite à tenir
Check cyclosporine trough levels and clinical response when ixekizumab is started or stopped. Monitor for infection.
Questions à poser à votre pharmacien
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Réservé aux membres Pro+
Débloquer la page complète
Créez un compte et lancez un essai Pro+ pour débloquer les conseils complets de prise en charge pour Cyclosporin et Ixekizumab, les notes complémentaires, le détail des données probantes et le vérificateur d'interactions pour une ordonnance complète.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Essayez Pro+ gratuitement pendant 7 jours sur le web. Sans carte.
Autres interactions de Cyclosporin
- Adenovirus types 4 and 7 live + Cyclosporin Contre-indiquée
- Aliskiren + Cyclosporin Contre-indiquée
- Bcg vaccine live + Cyclosporin Contre-indiquée
- Bosentan + Cyclosporin Contre-indiquée
- Cidofovir + Cyclosporin Contre-indiquée
- Cyclosporin + Dengue vaccine Contre-indiquée
Autres interactions de Ixekizumab
- Ixekizumab + Measles mumps and rubella vaccine Majeure
- Ixekizumab + Upadacitinib Majeure
- Ifosfamide + Ixekizumab Modérée
- Ixekizumab + Lomustine Modérée
- Carbamazepine + Ixekizumab Mineure
- Ethosuximide + Ixekizumab Mineure
Questions fréquentes
Can I take Cyclosporin with Ixekizumab?
MediHelp rates the interaction as minor. Cyclosporin and Ixekizumab have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Reduced inflammation during IL-17A blockade may restore CYP450 activity that was suppressed by cytokines, theoretically lowering cyclosporine concentrations. A clinically important effect has not been established. Combined immunosuppression also raises infection concerns.
How serious is the interaction between Cyclosporin and Ixekizumab?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check cyclosporine trough levels and clinical response when ixekizumab is started or stopped. Monitor for infection.
What other medicines interact with Cyclosporin?
MediHelp also lists interactions of Cyclosporin with, for example, Adenovirus types 4 and 7 live, Aliskiren, Bcg vaccine live. The full list is on the Cyclosporin page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
