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Interactions médicamenteuses

Lincomycin + Pancuronium

Gravité: Majeure

Lincomycin and Pancuronium: major interaction.

Dernière mise à jour

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Résumé

Lincomycin can potentiate pancuronium and prolong neuromuscular blockade. Delayed recovery and respiratory depression have been described with this class combination.

Ce que signifie cette interaction, en termes simples

Lincomycin and Pancuronium can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.

Lincomycin belongs to Anti Bacterial; Pancuronium belongs to Musculoskeletal.

Niveau de preuve: Moderate

Pourquoi elle survient

Lincomycin has weak intrinsic neuromuscular blocking activity that adds to pancuronium's effect.

Conduite à tenir

Titrate pancuronium with train-of-four monitoring and maintain ventilatory support until recovery is confirmed. Choose a different antibiotic if practical.

Questions à poser à votre pharmacien

  • Does the benefit of taking both outweigh the risk in my case?
  • Do I need any blood test, ECG or other check while on both?
  • What early warning signs should I watch for, and what should I do if they appear?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Questions fréquentes

Can I take Lincomycin with Pancuronium?

MediHelp rates the interaction as major. Lincomycin and Pancuronium can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Lincomycin can potentiate pancuronium and prolong neuromuscular blockade. Delayed recovery and respiratory depression have been described with this class combination.

How serious is the interaction between Lincomycin and Pancuronium?

MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Titrate pancuronium with train-of-four monitoring and maintain ventilatory support until recovery is confirmed. Choose a different antibiotic if practical.

What other medicines interact with Pancuronium?

MediHelp also lists interactions of Pancuronium with, for example, Amikacin, Bacitracin-neomycin-polymyxin, Capreomycin. The full list is on the Pancuronium page.

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Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.

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