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Interactions médicamenteuses

Oritavancin + Sirolimus

Gravité: Mineure

Oritavancin and Sirolimus: minor interaction.

Dernière mise à jour

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Résumé

Oritavancin is a weak CYP3A4 inducer in vitro and could marginally lower sirolimus concentrations. Since oritavancin is given as a single dose, any effect is likely small and short-lived.

Ce que signifie cette interaction, en termes simples

Oritavancin and Sirolimus have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Oritavancin belongs to Anti Bacterial; Sirolimus belongs to Miscellaneous.

Niveau de preuve: Low

Pourquoi elle survient

Weak CYP3A4 induction by oritavancin may modestly increase sirolimus clearance.

Conduite à tenir

No routine dose change is required. Check a sirolimus trough level if there is concern about reduced exposure.

Questions à poser à votre pharmacien

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Questions fréquentes

Can I take Oritavancin with Sirolimus?

MediHelp rates the interaction as minor. Oritavancin and Sirolimus have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Oritavancin is a weak CYP3A4 inducer in vitro and could marginally lower sirolimus concentrations. Since oritavancin is given as a single dose, any effect is likely small and short-lived.

How serious is the interaction between Oritavancin and Sirolimus?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine dose change is required. Check a sirolimus trough level if there is concern about reduced exposure.

What other medicines interact with Sirolimus?

MediHelp also lists interactions of Sirolimus with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Sirolimus page.

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Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.

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