Interazioni tra farmaci
Amiodarone + Moxifloxacin
Gravità: Controindicata
Amiodarone and Moxifloxacin: contraindicated interaction.
Ultimo aggiornamento
Per operatori sanitari — solo a scopo di riferimento. Questa pagina è una sintesi breve, non è un parere medico e non sostituisce il RCP ufficiale né il giudizio clinico. Verificare sempre prima di prescrivere o dispensare.
Il contenuto clinico di questa pagina è disponibile solo in inglese.
Sintesi
Both agents prolong the QT interval, and the combination markedly increases the risk of torsades de pointes. Amiodarone's long half-life means the risk persists after it is stopped.
Cosa significa questa interazione in parole semplici
Amiodarone and Moxifloxacin are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Amiodarone belongs to Cardiovascular; Moxifloxacin belongs to Anti Bacterial.
Perché avviene
Additive blockade of cardiac potassium channels (IKr) resulting in delayed repolarization.
Cosa fare
Avoid the combination and choose a non-QT-prolonging antibiotic. If it cannot be avoided, monitor ECG closely and keep potassium and magnesium within normal range.
Cosa chiedere al farmacista
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Per gli utenti Pro+
Sblocca la pagina completa
Crei un account e avvii una prova di Pro+ per sbloccare le indicazioni complete sulla gestione di Amiodarone e Moxifloxacin, le note aggiuntive, il dettaglio delle evidenze e il controllo delle interazioni per un'intera prescrizione.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Provi Pro+ gratis per 14 giorni sul web. Nessuna carta.
Altre interazioni di Moxifloxacin
- Arsenic trioxide + Moxifloxacin Controindicata
- Disopyramide + Moxifloxacin Controindicata
- Dofetilide + Moxifloxacin Controindicata
- Dronedarone + Moxifloxacin Controindicata
- Droperidol + Moxifloxacin Controindicata
- Ibutilide + Moxifloxacin Controindicata
Altre interazioni di Amiodarone
- Amiodarone + Amisulpride Controindicata
- Amiodarone + Arsenic trioxide Controindicata
- Amiodarone + Dofetilide Controindicata
- Amiodarone + Dronedarone Controindicata
- Amiodarone + Droperidol Controindicata
- Amiodarone + Eliglustat Controindicata
Domande frequenti
Can I take Amiodarone with Moxifloxacin?
MediHelp rates the interaction as contraindicated. Amiodarone and Moxifloxacin are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Both agents prolong the QT interval, and the combination markedly increases the risk of torsades de pointes. Amiodarone's long half-life means the risk persists after it is stopped.
How serious is the interaction between Amiodarone and Moxifloxacin?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination and choose a non-QT-prolonging antibiotic. If it cannot be avoided, monitor ECG closely and keep potassium and magnesium within normal range.
What other medicines interact with Moxifloxacin?
MediHelp also lists interactions of Moxifloxacin with, for example, Arsenic trioxide, Disopyramide, Dofetilide. The full list is on the Moxifloxacin page.
Monografie complete, posologie e verifica delle interazioni nell'app MediHelp
Apra il riferimento completo, verifichi le interazioni tra più farmaci e usi gli strumenti di posologia nell'app MediHelp.
