Interazioni tra farmaci
Arsenic trioxide + Moxifloxacin
Gravità: Controindicata
Arsenic trioxide and Moxifloxacin: contraindicated interaction.
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Sintesi
Arsenic trioxide causes QT prolongation and torsades de pointes and carries a boxed warning. Moxifloxacin adds further QT prolongation, so the combination should be avoided.
Cosa significa questa interazione in parole semplici
Arsenic trioxide and Moxifloxacin are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Arsenic trioxide belongs to Oncology; Moxifloxacin belongs to Anti Bacterial.
Perché avviene
Additive pharmacodynamic QT prolongation.
Cosa fare
Avoid the combination and use a non-QT-prolonging antibiotic. If unavoidable, keep potassium and magnesium replete and monitor ECGs frequently.
Cosa chiedere al farmacista
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Altre interazioni di Moxifloxacin
- Amiodarone + Moxifloxacin Controindicata
- Disopyramide + Moxifloxacin Controindicata
- Dofetilide + Moxifloxacin Controindicata
- Dronedarone + Moxifloxacin Controindicata
- Droperidol + Moxifloxacin Controindicata
- Ibutilide + Moxifloxacin Controindicata
Altre interazioni di Arsenic trioxide
- Amiodarone + Arsenic trioxide Controindicata
- Amisulpride + Arsenic trioxide Controindicata
- Arsenic trioxide + Clomipramine Controindicata
- Arsenic trioxide + Dronedarone Controindicata
- Arsenic trioxide + Fluphenazine Controindicata
- Arsenic trioxide + Gemifloxacin Controindicata
Domande frequenti
Can I take Arsenic trioxide with Moxifloxacin?
MediHelp rates the interaction as contraindicated. Arsenic trioxide and Moxifloxacin are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Arsenic trioxide causes QT prolongation and torsades de pointes and carries a boxed warning. Moxifloxacin adds further QT prolongation, so the combination should be avoided.
How serious is the interaction between Arsenic trioxide and Moxifloxacin?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination and use a non-QT-prolonging antibiotic. If unavoidable, keep potassium and magnesium replete and monitor ECGs frequently.
What other medicines interact with Moxifloxacin?
MediHelp also lists interactions of Moxifloxacin with, for example, Amiodarone, Disopyramide, Dofetilide. The full list is on the Moxifloxacin page.
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