Interazioni tra farmaci
Ibutilide + Moxifloxacin
Gravità: Controindicata
Ibutilide and Moxifloxacin: contraindicated interaction.
Ultimo aggiornamento
Per operatori sanitari — solo a scopo di riferimento. Questa pagina è una sintesi breve, non è un parere medico e non sostituisce il RCP ufficiale né il giudizio clinico. Verificare sempre prima di prescrivere o dispensare.
Il contenuto clinico di questa pagina è disponibile solo in inglese.
Sintesi
Ibutilide strongly prolongs repolarization and carries a substantial risk of torsades de pointes. Adding moxifloxacin further increases QT prolongation and arrhythmia risk.
Cosa significa questa interazione in parole semplici
Ibutilide and Moxifloxacin are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Ibutilide belongs to Cardiovascular; Moxifloxacin belongs to Anti Bacterial.
Perché avviene
Additive potassium channel blockade leading to delayed ventricular repolarization.
Cosa fare
Do not coadminister; use an alternative antibacterial while ibutilide is being used. Correct hypokalemia and hypomagnesemia and monitor ECG if exposure has occurred.
Cosa chiedere al farmacista
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Per gli utenti Pro+
Sblocca la pagina completa
Crei un account e avvii una prova di Pro+ per sbloccare le indicazioni complete sulla gestione di Ibutilide e Moxifloxacin, le note aggiuntive, il dettaglio delle evidenze e il controllo delle interazioni per un'intera prescrizione.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Provi Pro+ gratis per 14 giorni sul web. Nessuna carta.
Altre interazioni di Moxifloxacin
- Amiodarone + Moxifloxacin Controindicata
- Arsenic trioxide + Moxifloxacin Controindicata
- Disopyramide + Moxifloxacin Controindicata
- Dofetilide + Moxifloxacin Controindicata
- Dronedarone + Moxifloxacin Controindicata
- Droperidol + Moxifloxacin Controindicata
Altre interazioni di Ibutilide
- Amiodarone + Ibutilide Controindicata
- Amisulpride + Ibutilide Controindicata
- Chlorpromazine + Ibutilide Controindicata
- Clarithromycin + Ibutilide Controindicata
- Desipramine + Ibutilide Controindicata
- Dolasetron + Ibutilide Controindicata
Domande frequenti
Can I take Ibutilide with Moxifloxacin?
MediHelp rates the interaction as contraindicated. Ibutilide and Moxifloxacin are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Ibutilide strongly prolongs repolarization and carries a substantial risk of torsades de pointes. Adding moxifloxacin further increases QT prolongation and arrhythmia risk.
How serious is the interaction between Ibutilide and Moxifloxacin?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not coadminister; use an alternative antibacterial while ibutilide is being used. Correct hypokalemia and hypomagnesemia and monitor ECG if exposure has occurred.
What other medicines interact with Moxifloxacin?
MediHelp also lists interactions of Moxifloxacin with, for example, Amiodarone, Arsenic trioxide, Disopyramide. The full list is on the Moxifloxacin page.
Monografie complete, posologie e verifica delle interazioni nell'app MediHelp
Apra il riferimento completo, verifichi le interazioni tra più farmaci e usi gli strumenti di posologia nell'app MediHelp.
