Interazioni tra farmaci
Ceftazidime + Plazomicin
Gravità: Moderata
Ceftazidime and Plazomicin: moderate interaction.
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Sintesi
Plazomicin is nephrotoxic, ototoxic and can cause neuromuscular blockade, and concurrent use with ceftazidime may add to renal stress. The combination is sometimes used deliberately for resistant Gram-negative infection, but kidney function can deteriorate.
Cosa significa questa interazione in parole semplici
Ceftazidime and Plazomicin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Ceftazidime belongs to Anti Bacterial; Plazomicin belongs to Anti Bacterial.
Perché avviene
Additive nephrotoxic potential, with impaired renal function raising plazomicin exposure and ototoxic risk.
Cosa fare
Monitor serum creatinine frequently and use plazomicin therapeutic drug monitoring if available. Adjust doses to renal function and watch for hearing or balance changes.
Cosa chiedere al farmacista
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Altre interazioni di Ceftazidime
- Amikacin + Ceftazidime Moderata
- Ceftazidime + Cholera vaccine Moderata
- Ceftazidime + Dexamethasone-tobramycin Moderata
- Ceftazidime + Gentamicin Moderata
- Ceftazidime + Kanamycin Moderata
- Ceftazidime + Microbiota Moderata
Altre interazioni di Plazomicin
- Cefaclor + Plazomicin Moderata
- Cefadroxil + Plazomicin Moderata
- Cefalexin + Plazomicin Moderata
- Cefazolin + Plazomicin Moderata
- Cefditoren + Plazomicin Moderata
- Cefepime + Plazomicin Moderata
Domande frequenti
Can I take Ceftazidime with Plazomicin?
MediHelp rates the interaction as moderate. Ceftazidime and Plazomicin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Plazomicin is nephrotoxic, ototoxic and can cause neuromuscular blockade, and concurrent use with ceftazidime may add to renal stress. The combination is sometimes used deliberately for resistant Gram-negative infection, but kidney function can deteriorate.
How serious is the interaction between Ceftazidime and Plazomicin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine frequently and use plazomicin therapeutic drug monitoring if available. Adjust doses to renal function and watch for hearing or balance changes.
What other medicines interact with Ceftazidime?
MediHelp also lists interactions of Ceftazidime with, for example, Amikacin, Cholera vaccine, Dexamethasone-tobramycin. The full list is on the Ceftazidime page.
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