Interazioni tra farmaci
Certolizumab pegol + Rotavirus oral vaccine live
Gravità: Controindicata
Certolizumab pegol and Rotavirus oral vaccine live: contraindicated interaction.
Ultimo aggiornamento
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Sintesi
Oral rotavirus vaccine is a live attenuated virus. Infants exposed to certolizumab, such as through breast milk or in utero, or patients treated directly, may be at risk of vaccine-virus infection, though transfer of certolizumab is minimal.
Cosa significa questa interazione in parole semplici
Certolizumab pegol and Rotavirus oral vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Perché avviene
TNF inhibition impairs immune control of replicating live vaccine virus.
Cosa fare
Avoid rotavirus vaccine in patients receiving certolizumab. For infants of treated mothers, follow current specialist guidance, as certolizumab has minimal placental and milk transfer.
Cosa chiedere al farmacista
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Altre interazioni di Certolizumab pegol
- Adenovirus types 4 and 7 live + Certolizumab pegol Controindicata
- Bcg intravesical live + Certolizumab pegol Controindicata
- Bcg vaccine live + Certolizumab pegol Controindicata
- Certolizumab pegol + Influenza virus vaccine quadrivalent intranasal Controindicata
- Certolizumab pegol + Measles mumps and rubella vaccine Controindicata
- Certolizumab pegol + Measles mumps and rubella vaccine live Controindicata
Domande frequenti
Can I take Certolizumab pegol with Rotavirus oral vaccine live?
MediHelp rates the interaction as contraindicated. Certolizumab pegol and Rotavirus oral vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Oral rotavirus vaccine is a live attenuated virus. Infants exposed to certolizumab, such as through breast milk or in utero, or patients treated directly, may be at risk of vaccine-virus infection, though transfer of certolizumab is minimal.
How serious is the interaction between Certolizumab pegol and Rotavirus oral vaccine live?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid rotavirus vaccine in patients receiving certolizumab. For infants of treated mothers, follow current specialist guidance, as certolizumab has minimal placental and milk transfer.
What other medicines interact with Certolizumab pegol?
MediHelp also lists interactions of Certolizumab pegol with, for example, Adenovirus types 4 and 7 live, Bcg intravesical live, Bcg vaccine live. The full list is on the Certolizumab pegol page.
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