Interazioni tra farmaci
Chlorothiazide + Ergocalciferol
Gravità: Moderata
Chlorothiazide and Ergocalciferol: moderate interaction.
Ultimo aggiornamento
Per operatori sanitari — solo a scopo di riferimento. Questa pagina è una sintesi breve, non è un parere medico e non sostituisce il RCP ufficiale né il giudizio clinico. Verificare sempre prima di prescrivere o dispensare.
Il contenuto clinico di questa pagina è disponibile solo in inglese.
Sintesi
Thiazide diuretics reduce urinary calcium excretion, and vitamin D increases calcium absorption from the gut. Combined use can lead to hypercalcemia, especially with high vitamin D doses or underlying hyperparathyroidism or renal disease.
Cosa significa questa interazione in parole semplici
Chlorothiazide and Ergocalciferol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Chlorothiazide belongs to Cardiovascular; Ergocalciferol belongs to Musculoskeletal.
Perché avviene
Thiazides increase renal tubular calcium reabsorption, adding to vitamin D-mediated increases in calcium absorption.
Cosa fare
Monitor serum calcium at baseline and periodically during therapy. Reduce the vitamin D dose or reconsider the thiazide if hypercalcemia occurs.
Cosa chiedere al farmacista
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Per gli utenti Pro+
Sblocca la pagina completa
Crei un account e avvii una prova di Pro+ per sbloccare le indicazioni complete sulla gestione di Chlorothiazide e Ergocalciferol, le note aggiuntive, il dettaglio delle evidenze e il controllo delle interazioni per un'intera prescrizione.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Provi Pro+ gratis per 14 giorni sul web. Nessuna carta.
Altre interazioni di Ergocalciferol
- Aluminum hydroxide + Ergocalciferol Moderata
- Calcium acetate + Ergocalciferol Moderata
- Calcium carbonate + Ergocalciferol Moderata
- Calcium chloride + Ergocalciferol Moderata
- Calcium citrate + Ergocalciferol Moderata
- Calcium gluconate + Ergocalciferol Moderata
Altre interazioni di Chlorothiazide
- Amlodipine-olmesartan-hydrochlorothiazide + Chlorothiazide Maggiore
- Candesartan-hydrochlorothiazide + Chlorothiazide Maggiore
- Chlorothiazide + Hydrochlorothiazide-lisinopril Maggiore
- Chlorothiazide + Hydrochlorothiazide-losartan Maggiore
- Chlorothiazide + Lithium Maggiore
- Chlorothiazide + Sotalol Maggiore
Domande frequenti
Can I take Chlorothiazide with Ergocalciferol?
MediHelp rates the interaction as moderate. Chlorothiazide and Ergocalciferol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Thiazide diuretics reduce urinary calcium excretion, and vitamin D increases calcium absorption from the gut. Combined use can lead to hypercalcemia, especially with high vitamin D doses or underlying hyperparathyroidism or renal disease.
How serious is the interaction between Chlorothiazide and Ergocalciferol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum calcium at baseline and periodically during therapy. Reduce the vitamin D dose or reconsider the thiazide if hypercalcemia occurs.
What other medicines interact with Ergocalciferol?
MediHelp also lists interactions of Ergocalciferol with, for example, Aluminum hydroxide, Calcium acetate, Calcium carbonate. The full list is on the Ergocalciferol page.
Monografie complete, posologie e verifica delle interazioni nell'app MediHelp
Apra il riferimento completo, verifichi le interazioni tra più farmaci e usi gli strumenti di posologia nell'app MediHelp.
