Interazioni tra farmaci
Colchicine + Fluvastatin
Gravità: Moderata
Colchicine and Fluvastatin: moderate interaction.
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Sintesi
Both drugs can cause myopathy, and the combination has been linked to rhabdomyolysis. Risk is greater in older patients and those with renal impairment.
Cosa significa questa interazione in parole semplici
Colchicine and Fluvastatin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Colchicine belongs to Genitourinary; Fluvastatin belongs to Cardiovascular.
Perché avviene
Additive myotoxicity.
Cosa fare
Monitor for muscle pain, weakness and dark urine, and check creatine kinase if symptoms occur. Consider temporary statin interruption during colchicine courses in high-risk patients.
Cosa chiedere al farmacista
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Altre interazioni di Colchicine
- Clarithromycin + Colchicine Controindicata
- Cobicistat + Colchicine Controindicata
- Colchicine + Cyclosporine Controindicata
- Colchicine + Ensitrelvir Controindicata
- Colchicine + Levoketoconazole Controindicata
- Colchicine + Nirmatrelvir Controindicata
Altre interazioni di Fluvastatin
- Cyclosporine + Fluvastatin Maggiore
- Cyclosporin + Fluvastatin Maggiore
- Fluvastatin + Gemfibrozil Maggiore
- Fluvastatin + Letermovir Maggiore
- Fluvastatin + Red yeast rice Maggiore
- Apalutamide + Fluvastatin Moderata
Domande frequenti
Can I take Colchicine with Fluvastatin?
MediHelp rates the interaction as moderate. Colchicine and Fluvastatin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs can cause myopathy, and the combination has been linked to rhabdomyolysis. Risk is greater in older patients and those with renal impairment.
How serious is the interaction between Colchicine and Fluvastatin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for muscle pain, weakness and dark urine, and check creatine kinase if symptoms occur. Consider temporary statin interruption during colchicine courses in high-risk patients.
What other medicines interact with Colchicine?
MediHelp also lists interactions of Colchicine with, for example, Clarithromycin, Cobicistat, Cyclosporine. The full list is on the Colchicine page.
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