Interazioni tra farmaci
Colestipol + Vitamin k1
Gravità: Moderata
Colestipol and Vitamin k1: moderate interaction.
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Sintesi
Colestipol is a bile acid sequestrant that impairs absorption of fat-soluble vitamins, including vitamin K. Prolonged use may lower vitamin K status and, in susceptible patients, contribute to prolonged clotting times or bleeding.
Cosa significa questa interazione in parole semplici
Colestipol and Vitamin k1 can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Colestipol belongs to Cardiovascular; Vitamin k1 belongs to Cardiovascular.
Perché avviene
Colestipol binds bile acids in the gut, reducing micelle formation and absorption of oral vitamin K.
Cosa fare
Give oral vitamin K at least 4 hours before or after colestipol. Monitor INR or prothrombin time in patients on long-term colestipol or with other risk factors for deficiency.
Cosa chiedere al farmacista
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Altre interazioni di Vitamin k1
- Vitamin k1 + Warfarin Maggiore
- Cholestyramine + Vitamin k1 Moderata
- Ketorolac intranasal + Vitamin k1 Moderata
- Mineral oil + Vitamin k1 Moderata
- Orlistat + Vitamin k1 Moderata
- Aescin + Vitamin k1 Minore
Altre interazioni di Colestipol
- Amlodipine-hydrochlorothiazide-valsartan + Colestipol Moderata
- Amlodipine-olmesartan-hydrochlorothiazide + Colestipol Moderata
- Atenolol-chlorthalidone + Colestipol Moderata
- Azilsartan-chlorthalidone + Colestipol Moderata
- Candesartan-hydrochlorothiazide + Colestipol Moderata
- Captopril-hydrochlorothiazide + Colestipol Moderata
Domande frequenti
Can I take Colestipol with Vitamin k1?
MediHelp rates the interaction as moderate. Colestipol and Vitamin k1 can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Colestipol is a bile acid sequestrant that impairs absorption of fat-soluble vitamins, including vitamin K. Prolonged use may lower vitamin K status and, in susceptible patients, contribute to prolonged clotting times or bleeding.
How serious is the interaction between Colestipol and Vitamin k1?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give oral vitamin K at least 4 hours before or after colestipol. Monitor INR or prothrombin time in patients on long-term colestipol or with other risk factors for deficiency.
What other medicines interact with Vitamin k1?
MediHelp also lists interactions of Vitamin k1 with, for example, Warfarin, Cholestyramine, Ketorolac intranasal. The full list is on the Vitamin k1 page.
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