Interazioni tra farmaci
Dexbrompheniramine + Fentanyl
Gravità: Moderata
Dexbrompheniramine and Fentanyl: moderate interaction.
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Sintesi
Dexbrompheniramine is a sedating antihistamine that adds to fentanyl's CNS depression. The combination can cause marked drowsiness and impaired psychomotor function, and respiratory depression is possible with higher doses.
Cosa significa questa interazione in parole semplici
Dexbrompheniramine and Fentanyl can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Dexbrompheniramine belongs to Respiratory; Fentanyl belongs to Musculoskeletal.
Perché avviene
Additive CNS depression from an opioid and a sedating first-generation antihistamine.
Cosa fare
Use the lowest effective doses and monitor for sedation and respiratory depression. Advise patients to avoid alcohol and driving.
Cosa chiedere al farmacista
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Altre interazioni di Fentanyl
- Alvimopan + Fentanyl Controindicata
- Fentanyl + Isocarboxazid Controindicata
- Fentanyl + Olanzapine / samidorphan Controindicata
- Fentanyl + Phenelzine Controindicata
- Fentanyl + Tranylcypromine Controindicata
- Alfentanil + Fentanyl Maggiore
Altre interazioni di Dexbrompheniramine
- Amisulpride + Dexbrompheniramine Moderata
- Asenapine + Dexbrompheniramine Moderata
- Brexpiprazole + Dexbrompheniramine Moderata
- Brimonidine + Dexbrompheniramine Moderata
- Brivaracetam + Dexbrompheniramine Moderata
- Cariprazine + Dexbrompheniramine Moderata
Domande frequenti
Can I take Dexbrompheniramine with Fentanyl?
MediHelp rates the interaction as moderate. Dexbrompheniramine and Fentanyl can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Dexbrompheniramine is a sedating antihistamine that adds to fentanyl's CNS depression. The combination can cause marked drowsiness and impaired psychomotor function, and respiratory depression is possible with higher doses.
How serious is the interaction between Dexbrompheniramine and Fentanyl?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use the lowest effective doses and monitor for sedation and respiratory depression. Advise patients to avoid alcohol and driving.
What other medicines interact with Fentanyl?
MediHelp also lists interactions of Fentanyl with, for example, Alvimopan, Isocarboxazid, Olanzapine / samidorphan. The full list is on the Fentanyl page.
Monografie complete, posologie e verifica delle interazioni nell'app MediHelp
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