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Interazioni tra farmaci

Dexmethylphenidate + Phenelzine

Gravità: Controindicata

Dexmethylphenidate and Phenelzine: contraindicated interaction.

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Sintesi

Dexmethylphenidate with MAO inhibitors may cause hypertensive crisis. Severe headache, very high blood pressure and cerebrovascular events are possible.

Cosa significa questa interazione in parole semplici

Dexmethylphenidate and Phenelzine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Dexmethylphenidate belongs to Central Nervous System; Phenelzine belongs to Central Nervous System.

Livello di evidenza: High

Perché avviene

MAO inhibition increases catecholamine stores, and dexmethylphenidate increases synaptic catecholamines, producing an exaggerated pressor response.

Cosa fare

Do not use during phenelzine therapy or within 14 days of stopping it. Select a non-stimulant alternative.

Cosa chiedere al farmacista

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Domande frequenti

Can I take Dexmethylphenidate with Phenelzine?

MediHelp rates the interaction as contraindicated. Dexmethylphenidate and Phenelzine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Dexmethylphenidate with MAO inhibitors may cause hypertensive crisis. Severe headache, very high blood pressure and cerebrovascular events are possible.

How serious is the interaction between Dexmethylphenidate and Phenelzine?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use during phenelzine therapy or within 14 days of stopping it. Select a non-stimulant alternative.

What other medicines interact with Phenelzine?

MediHelp also lists interactions of Phenelzine with, for example, 5-HTP, Amitriptyline, Amoxapine. The full list is on the Phenelzine page.

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