Interazioni tra farmaci
Dexmethylphenidate + Isocarboxazid
Gravità: Controindicata
Dexmethylphenidate and Isocarboxazid: contraindicated interaction.
Ultimo aggiornamento
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Sintesi
Dexmethylphenidate with an MAOI can precipitate hypertensive crisis. Labeling prohibits use during or within 14 days of MAOI therapy.
Cosa significa questa interazione in parole semplici
Dexmethylphenidate and Isocarboxazid are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Dexmethylphenidate belongs to Central Nervous System; Isocarboxazid belongs to Central Nervous System.
Perché avviene
MAO inhibition combined with stimulant-induced catecholamine release and reuptake blockade produces excessive adrenergic stimulation.
Cosa fare
Avoid the combination and allow 14 days after stopping the MAOI before dexmethylphenidate. Consider a non-stimulant ADHD agent only after appropriate washout.
Cosa chiedere al farmacista
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Altre interazioni di Isocarboxazid
- 5-HTP + Isocarboxazid Controindicata
- Amitriptyline + Isocarboxazid Controindicata
- Amobarbital + Isocarboxazid Controindicata
- Amoxapine + Isocarboxazid Controindicata
- Apraclonidine + Isocarboxazid Controindicata
- Atomoxetine + Isocarboxazid Controindicata
Altre interazioni di Dexmethylphenidate
- Dexmethylphenidate + Linezolid Controindicata
- Dexmethylphenidate + Phenelzine Controindicata
- Dexmethylphenidate + Procarbazine Controindicata
- Dexmethylphenidate + Rasagiline Controindicata
- Dexmethylphenidate + Safinamide Controindicata
- Dexmethylphenidate + Selegiline Controindicata
Domande frequenti
Can I take Dexmethylphenidate with Isocarboxazid?
MediHelp rates the interaction as contraindicated. Dexmethylphenidate and Isocarboxazid are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Dexmethylphenidate with an MAOI can precipitate hypertensive crisis. Labeling prohibits use during or within 14 days of MAOI therapy.
How serious is the interaction between Dexmethylphenidate and Isocarboxazid?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination and allow 14 days after stopping the MAOI before dexmethylphenidate. Consider a non-stimulant ADHD agent only after appropriate washout.
What other medicines interact with Isocarboxazid?
MediHelp also lists interactions of Isocarboxazid with, for example, 5-HTP, Amitriptyline, Amobarbital. The full list is on the Isocarboxazid page.
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