Interazioni tra farmaci
Dexmethylphenidate + Selegiline
Gravità: Controindicata
Dexmethylphenidate and Selegiline: contraindicated interaction.
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Sintesi
MAO inhibitors combined with methylphenidate-type stimulants can provoke severe hypertensive crisis. Labeling contraindicates dexmethylphenidate during MAOI therapy and for 14 days afterward.
Cosa significa questa interazione in parole semplici
Dexmethylphenidate and Selegiline are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Dexmethylphenidate belongs to Central Nervous System; Selegiline belongs to Central Nervous System.
Perché avviene
The stimulant releases catecholamines, and MAO inhibition prevents their degradation, so they accumulate.
Cosa fare
Do not combine. Allow at least 14 days after stopping the MAOI before starting dexmethylphenidate.
Cosa chiedere al farmacista
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Altre interazioni di Selegiline
- Amitriptyline + Selegiline Controindicata
- Amoxapine + Selegiline Controindicata
- Atomoxetine + Selegiline Controindicata
- Benzphetamine + Selegiline Controindicata
- Brimonidine + Selegiline Controindicata
- Buprenorphine long-acting + Selegiline Controindicata
Altre interazioni di Dexmethylphenidate
- Dexmethylphenidate + Isocarboxazid Controindicata
- Dexmethylphenidate + Linezolid Controindicata
- Dexmethylphenidate + Phenelzine Controindicata
- Dexmethylphenidate + Procarbazine Controindicata
- Dexmethylphenidate + Rasagiline Controindicata
- Dexmethylphenidate + Safinamide Controindicata
Domande frequenti
Can I take Dexmethylphenidate with Selegiline?
MediHelp rates the interaction as contraindicated. Dexmethylphenidate and Selegiline are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. MAO inhibitors combined with methylphenidate-type stimulants can provoke severe hypertensive crisis. Labeling contraindicates dexmethylphenidate during MAOI therapy and for 14 days afterward.
How serious is the interaction between Dexmethylphenidate and Selegiline?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not combine. Allow at least 14 days after stopping the MAOI before starting dexmethylphenidate.
What other medicines interact with Selegiline?
MediHelp also lists interactions of Selegiline with, for example, Amitriptyline, Amoxapine, Atomoxetine. The full list is on the Selegiline page.
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