Interazioni tra farmaci
Dexmethylphenidate + Rasagiline
Gravità: Controindicata
Dexmethylphenidate and Rasagiline: contraindicated interaction.
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Sintesi
Stimulants such as dexmethylphenidate given with MAO inhibitors may cause hypertensive crisis. Labeling contraindicates use during and for 14 days after MAO inhibitor therapy.
Cosa significa questa interazione in parole semplici
Dexmethylphenidate and Rasagiline are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Dexmethylphenidate belongs to Central Nervous System; Rasagiline belongs to Central Nervous System.
Perché avviene
Dexmethylphenidate increases synaptic catecholamines and MAO inhibition prevents their breakdown, causing additive pressor effects.
Cosa fare
Avoid the combination and separate by at least 14 days after stopping the MAO inhibitor. Use a non-stimulant alternative if needed.
Cosa chiedere al farmacista
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Altre interazioni di Rasagiline
- Atomoxetine + Rasagiline Controindicata
- Brimonidine + Rasagiline Controindicata
- Bupropion-naltrexone + Rasagiline Controindicata
- Bupropion + Rasagiline Controindicata
- Clomipramine + Rasagiline Controindicata
- Desvenlafaxine + Rasagiline Controindicata
Altre interazioni di Dexmethylphenidate
- Dexmethylphenidate + Isocarboxazid Controindicata
- Dexmethylphenidate + Linezolid Controindicata
- Dexmethylphenidate + Phenelzine Controindicata
- Dexmethylphenidate + Procarbazine Controindicata
- Dexmethylphenidate + Safinamide Controindicata
- Dexmethylphenidate + Selegiline Controindicata
Domande frequenti
Can I take Dexmethylphenidate with Rasagiline?
MediHelp rates the interaction as contraindicated. Dexmethylphenidate and Rasagiline are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Stimulants such as dexmethylphenidate given with MAO inhibitors may cause hypertensive crisis. Labeling contraindicates use during and for 14 days after MAO inhibitor therapy.
How serious is the interaction between Dexmethylphenidate and Rasagiline?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination and separate by at least 14 days after stopping the MAO inhibitor. Use a non-stimulant alternative if needed.
What other medicines interact with Rasagiline?
MediHelp also lists interactions of Rasagiline with, for example, Atomoxetine, Brimonidine, Bupropion-naltrexone. The full list is on the Rasagiline page.
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