Interazioni tra farmaci
Linezolid + Ozanimod
Gravità: Controindicata
Linezolid and Ozanimod: contraindicated interaction.
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Sintesi
Ozanimod active metabolites are formed through MAO-B and may inhibit MAO, and linezolid is an MAO inhibitor. The combination may cause hypertensive crisis or serotonergic toxicity.
Cosa significa questa interazione in parole semplici
Linezolid and Ozanimod are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Linezolid belongs to Anti Bacterial; Ozanimod belongs to Central Nervous System.
Perché avviene
Additive MAO inhibition and altered ozanimod metabolite exposure.
Cosa fare
Avoid concurrent use and choose an alternative antibiotic. If unavoidable, monitor blood pressure and for serotonin toxicity.
Cosa chiedere al farmacista
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Altre interazioni di Linezolid
- Amoxapine + Linezolid Controindicata
- Atomoxetine + Linezolid Controindicata
- Benzphetamine + Linezolid Controindicata
- Brimonidine + Linezolid Controindicata
- Bupropion-naltrexone + Linezolid Controindicata
- Bupropion + Linezolid Controindicata
Altre interazioni di Ozanimod
- Isocarboxazid + Ozanimod Controindicata
- Ozanimod + Phenelzine Controindicata
- Ozanimod + Procarbazine Controindicata
- Ozanimod + Rasagiline Controindicata
- Ozanimod + Safinamide Controindicata
- Ozanimod + Tranylcypromine Controindicata
Domande frequenti
Can I take Linezolid with Ozanimod?
MediHelp rates the interaction as contraindicated. Linezolid and Ozanimod are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Ozanimod active metabolites are formed through MAO-B and may inhibit MAO, and linezolid is an MAO inhibitor. The combination may cause hypertensive crisis or serotonergic toxicity.
How serious is the interaction between Linezolid and Ozanimod?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use and choose an alternative antibiotic. If unavoidable, monitor blood pressure and for serotonin toxicity.
What other medicines interact with Linezolid?
MediHelp also lists interactions of Linezolid with, for example, Amoxapine, Atomoxetine, Benzphetamine. The full list is on the Linezolid page.
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