医薬品リファレンス
Clodronate
Clodronate is a medicine in the class musculoskeletal. It is used for hypercalcemia of malignancy.
- 薬効分類: Musculoskeletal
- 効能・効果: hypercalcemia of malignancy
医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。
このページの臨床コンテンツは英語でのみ提供されています。
要点
- 薬効分類
- Musculoskeletal
- 一般的な剤形
- 注射剤
- 一般的な規格
- 60 mg/ml, 400 mg
- 商品名
- 2
- 国・市場
- 1
何に使われるか
作用のしくみ
Bisphosphonate; binds to hydroxyapatite crystals in bone and inhibits osteoclast-mediated bone resorption; decreases mineral release and collagen or matrix breakdown in bone
成人の通常用量（添付文書の要約）
Oral: The recommended daily dose is 2 tablets (1600mg sodium clodronate) taken as a single dose. Not recommended to exceed 3200 mg daily.
妊娠と授乳
- 妊娠
- Unsafe Bisphosphonate: binds to bone, and animal data show it crosses the placenta; it could affect fetal bone and calcium. Human data are limited. Not recommended in pregnancy or in women not using effective contraception.
- 授乳
- Unknown Not known if it passes into milk; little would be absorbed by the infant. The label says a risk cannot be excluded and to stop breastfeeding during treatment.
報告されている副作用
- Vomiting
- Diarrhea
- Nausea
- Bronchospasm
- Hypocalcaemia
- Increased AST
注意が必要な方
- While on treatment, these patients should avoid invasive dental procedures if possible.
- During bisphosphonate treatment patients should be advised to report any thigh, hip or groin pain and any patient presenting with such symptoms should be evaluated.
妊娠中または授乳中であること、腎臓や肝臓の病気、アレルギー、ほかに使用しているすべての薬やサプリメントについて、薬剤師または医師にお伝えください。
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Clodronateの完全なモノグラフ（用量、妊娠・授乳、副作用、警告、すべての相互作用）を表示できます。
- Dosing by age, kidney and liver function, and further dose lines
- Paediatric dosing
- Dosing in older adults
- Patient counselling points
- Food interactions
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同じ分類のほかの薬剤
よくある質問
What is Clodronate used for?
Clodronate is a medicine in the class musculoskeletal. It is used for Hypercalcemia of malignancy, Osteolytic bone lesions of MM, Osteolytic bone metastases of BC.
What side effects have been reported with Clodronate?
Vomiting, Diarrhea, Nausea, Bronchospasm, Hypocalcaemia, Increased AST.
Can Clodronate be taken in pregnancy or while breastfeeding?
Pregnancy: Unsafe. Bisphosphonate: binds to bone, and animal data show it crosses the placenta; it could affect fetal bone and calcium. Human data are limited. Not recommended in pregnancy or in women not using effective contraception. Breastfeeding: Unknown. Not known if it passes into milk; little would be absorbed by the infant. The label says a risk cannot be excluded and to stop breastfeeding during treatment.
What does Clodronate interact with?
MediHelp does not list a checked interaction for Clodronate yet. Always tell your pharmacist about every medicine you take.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
