医薬品リファレンス
Oxytetracycline
Oxytetracycline is a medicine in the class anti bacterial. It is used for bacterial conjunctivitis.
- 薬効分類: Anti Bacterial
- 効能・効果: bacterial conjunctivitis
最終更新日
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要点
- 薬効分類
- Anti Bacterial
- 一般的な剤形
- カプセル剤
- 一般的な規格
- 0.5%, 250 mg, 250 mg/3 ml
- 既知の相互作用
- 29 (併用禁忌: 1 · 中等度: 26 · 軽度: 2)
- 商品名
- 4
- 国・市場
- 2
何に使われるか
作用のしくみ
Inhibits bacterial protein synthesis by binding with 30S and possibly 50S ribosomal subunit(s)
成人の通常用量（添付文書の要約）
Chronic Bronchitis, Acute Exacerbation (Usual daily dose): 500 mg PO q12hr or 250 mg PO q6hr (ie, 1000 mg/day)
妊娠と授乳
- 妊娠
- Unsafe Tetracyclines can stain the baby's teeth and affect bone growth once tooth mineralisation starts (about 15 to 16 weeks), and high doses have caused liver toxicity in pregnant women. Avoid oral or injected oxytetracycline in pregnancy; use a safer antibiotic. Skin or eye use gives little absorption.
- 授乳
- Safe Labels advise avoiding breastfeeding. LactMed is more reassuring: milk levels are low and milk calcium limits absorption, so short courses are probably acceptable; avoid prolonged or repeated courses. Watch the infant for rash, diarrhoea or thrush.
報告されている副作用
- Nausea
- Anorexia
- Anemia
- Thrombocytopenia
- Increased BUN (dose-related)
注意が必要な方
- Absorption is adversely affected by milk, antacids and aluminium, calcium, iron, magnesium and zinc salts.
- Tetracyclines depress plasma prothrombin activity, therefore reduced dosages of concurrent anticoagulants may be required.
- Special care should be taken when treating the elderly.
妊娠中または授乳中であること、腎臓や肝臓の病気、アレルギー、ほかに使用しているすべての薬やサプリメントについて、薬剤師または医師にお伝えください。
主な相互作用 (29)
- Isotretinoin + Oxytetracycline Contraindicated
- Aluminum hydroxide + Oxytetracycline Moderate
- Ampicillin + Oxytetracycline Moderate
- Ampicillin-sulbactam + Oxytetracycline Moderate
- Atracurium + Oxytetracycline Moderate
- Bismuth subsalicylate + Oxytetracycline Moderate
- Calcium + Oxytetracycline Moderate
- Calcium carbonate + Oxytetracycline Moderate
- Carbonyl iron + Oxytetracycline Moderate
- Cholestyramine + Oxytetracycline Moderate
Pro+会員向け
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アカウントを作成してPro+トライアルを始めると、Oxytetracyclineの完全なモノグラフ（用量、妊娠・授乳、副作用、警告、すべての相互作用）を表示できます。
- Dosing by age, kidney and liver function, and further dose lines
- Paediatric dosing
- Patient counselling points
- Food interactions
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同じ分類のほかの薬剤
よくある質問
What is Oxytetracycline used for?
Oxytetracycline is a medicine in the class anti bacterial. It is used for Bacterial conjunctivitis, Respiratory tract infections, Sexually transmitted infections, Skin infections, Urinary tract infections.
What side effects have been reported with Oxytetracycline?
Nausea, Anorexia, Anemia, Thrombocytopenia, Increased BUN (dose-related).
Can Oxytetracycline be taken in pregnancy or while breastfeeding?
Pregnancy: Unsafe. Tetracyclines can stain the baby's teeth and affect bone growth once tooth mineralisation starts (about 15 to 16 weeks), and high doses have caused liver toxicity in pregnant women. Avoid oral or injected oxytetracycline in pregnancy; use a safer antibiotic. Skin or eye use gives little absorption. Breastfeeding: Safe. Labels advise avoiding breastfeeding. LactMed is more reassuring: milk levels are low and milk calcium limits absorption, so short courses are probably acceptable; avoid prolonged or repeated courses. Watch the infant for rash, diarrhoea or thrush.
What does Oxytetracycline interact with?
MediHelp lists 29 known interactions for Oxytetracycline. Contraindicated: 1 · Moderate: 26 · Minor: 2. The most serious include Isotretinoin, Aluminum hydroxide, Ampicillin.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
