相互作用
Amiodarone + Thalidomide
重症度: 中等度
Amiodarone and Thalidomide: moderate interaction.
最終更新日
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概要
Both thalidomide and long-term amiodarone can cause peripheral neuropathy. Concurrent use may raise the risk of sensory or motor nerve damage. Thalidomide can also cause bradycardia, which may add to amiodarone's effects on heart rate.
この相互作用をわかりやすく説明すると
Amiodarone and Thalidomide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amiodarone belongs to Cardiovascular; Thalidomide belongs to Miscellaneous.
なぜ起こるのか
Additive neurotoxicity; additive bradycardic effects.
対処法
Perform periodic neurological assessments and monitor heart rate and ECG. Modify therapy if neuropathy or symptomatic bradycardia develops.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、AmiodaroneとThalidomideの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Thalidomideのその他の相互作用
Amiodaroneのその他の相互作用
よくある質問
Can I take Amiodarone with Thalidomide?
MediHelp rates the interaction as moderate. Amiodarone and Thalidomide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both thalidomide and long-term amiodarone can cause peripheral neuropathy. Concurrent use may raise the risk of sensory or motor nerve damage. Thalidomide can also cause bradycardia, which may add to amiodarone's effects on heart rate.
How serious is the interaction between Amiodarone and Thalidomide?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Perform periodic neurological assessments and monitor heart rate and ECG. Modify therapy if neuropathy or symptomatic bradycardia develops.
What other medicines interact with Thalidomide?
MediHelp also lists interactions of Thalidomide with, for example, Bortezomib, Carbamazepine, Griseofulvin. The full list is on the Thalidomide page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
