相互作用
Amisulpride + Lefamulin
重症度: 重大
Amisulpride and Lefamulin: major interaction.
最終更新日
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概要
Lefamulin can prolong the QT interval, and amisulpride adds to this effect. Combined use raises the risk of arrhythmia such as torsades de pointes.
この相互作用をわかりやすく説明すると
Amisulpride and Lefamulin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Amisulpride belongs to Central Nervous System; Lefamulin belongs to Anti Bacterial.
なぜ起こるのか
Additive prolongation of cardiac repolarization.
対処法
Choose a non-QT-prolonging antibiotic if feasible. If coadministered, obtain ECG monitoring and correct electrolytes.
薬剤師に尋ねること
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、AmisulprideとLefamulinの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Amisulprideのその他の相互作用
Lefamulinのその他の相互作用
よくある質問
Can I take Amisulpride with Lefamulin?
MediHelp rates the interaction as major. Amisulpride and Lefamulin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Lefamulin can prolong the QT interval, and amisulpride adds to this effect. Combined use raises the risk of arrhythmia such as torsades de pointes.
How serious is the interaction between Amisulpride and Lefamulin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Choose a non-QT-prolonging antibiotic if feasible. If coadministered, obtain ECG monitoring and correct electrolytes.
What other medicines interact with Amisulpride?
MediHelp also lists interactions of Amisulpride with, for example, Amiodarone, Arsenic trioxide, Disopyramide. The full list is on the Amisulpride page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
