相互作用
Amisulpride + Vandetanib
重症度: 併用禁忌
Amisulpride and Vandetanib: contraindicated interaction.
最終更新日
医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。
このページの臨床コンテンツは英語でのみ提供されています。
概要
Vandetanib has a boxed warning for QT prolongation, torsades de pointes, and sudden death, and its use with other QT-prolonging drugs is to be avoided. Amisulpride would add to this risk.
この相互作用をわかりやすく説明すると
Amisulpride and Vandetanib are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Amisulpride belongs to Central Nervous System; Vandetanib belongs to Oncology.
なぜ起こるのか
Additive QT prolongation through delayed cardiac repolarization.
対処法
Do not combine; use a non-QT-prolonging alternative to amisulpride. If vandetanib treatment is essential, stop amisulpride.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、AmisulprideとVandetanibの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
WebでPro+を14日間無料でお試し。カード登録不要。
Amisulprideのその他の相互作用
Vandetanibのその他の相互作用
よくある質問
Can I take Amisulpride with Vandetanib?
MediHelp rates the interaction as contraindicated. Amisulpride and Vandetanib are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Vandetanib has a boxed warning for QT prolongation, torsades de pointes, and sudden death, and its use with other QT-prolonging drugs is to be avoided. Amisulpride would add to this risk.
How serious is the interaction between Amisulpride and Vandetanib?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not combine; use a non-QT-prolonging alternative to amisulpride. If vandetanib treatment is essential, stop amisulpride.
What other medicines interact with Amisulpride?
MediHelp also lists interactions of Amisulpride with, for example, Amiodarone, Arsenic trioxide, Disopyramide. The full list is on the Amisulpride page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
